substantially limited substantially limits substantially longer substantially lower substantially modified substantially more substantially opposite substantially parallel substantially perpendicular substantially pure substantially rebuilt substantially reduce substantially reduced substantially renovated substantially revised substantially same substantially similar substantially simultaneously substantially smaller substantially the same substantially the whole substantially unchanged substantiate substantiate it substantiated substantiated cases substantiated complaints substantiates substantiation substantiation of claims substantive substantive activities substantive amendments substantive and administrative substantive and procedural substantive areas substantive aspects substantive change substantive changes substantive comments substantive consolidation substantive content substantive criminal law substantive debate substantive discussion substantive discussions substantive elements substantive equality substantive examination substantive information substantive issue substantive issues substantive items substantive law substantive matters substantive patent substantive position substantive progress substantive provisions substantive questions substantive recommendations substantive report substantive requirements substantive rights substantive rules substantive servicing substantive session substantive support substantive theme substantive topics substantive work substantively substantivity substation substation automation substations substep substeps substituent substituent group substituent groups substituents substitutable substitute substitute appearance substitute appearances substitute can substitute english substitute for a good substitute for butter substitute for coffee substitute for hard substitute for human substitute for insulin substitute for it substitute for love substitute for meat substitute for medical substitute for other