Examples of 'a-msh' in a sentence
Meaning of "a-msh"
A-msh (adjective): This term does not have a commonly recognized definition in English. It may be specific to a certain context or language
How to use "a-msh" in a sentence
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a-msh
Also a-MSH induces pigment formation in skin.
Several derivatives of a-MSH have been synthesized.
Relative binding was determined by competitive inhibition using a-MSH.
Compared to a-MSH said peptides have several advantages.
The peptides of the invention are termed a-MSH analogues.
It is known that a-MSH concentrations are elevated in patients on chronic hemodialysis.
This example strongly implies that viral replication is affected by a-MSH.
It is known that a-MSH concentrations are elevated in patients on chronic haemodialysis.
The compounds can include those that enhance a-MSH activity.
Other cyclic and linear a-MSH peptides also have been studied.
The a-MSH peptide too is ascribed an important role in cutaneous biology.
This is especially important because a-MSH is known to inhibit neutrophil chemotaxis.
We recently found that human duodenal cells produce a-MSH in culture.
The efficacy of native a-MSH was compared to a known corticosteroid therapy, dexamethasone.
This example illustrates the biological functional equivalents of a-MSH and / or its derivatives.
See also
Among MCs, it was reported that a-MSH acts as a neurotransmitter or neuromodulator in the brain.
The possibility of modifying the dietary intake by changing the concentration in autoantibody against a-MSH.
This suggests that endogenous a-MSH has a physiological role in natural immunity.
Dopamine also increases the activity of POMC neurons to secrete a-MSH.
This carrier carrying the solvated a-MSH derivatives are then stored in a pressurized canister.
MCH also inhibits release of ACTH thus acting as an antagonist of a-MSH.
The efficacy of native a-MSH treatment in the murine posterior uveitis model was evaluated.
Brief Description of the Drawings Figure 1 shows reduction of uveitis by native a-MSH.
Many of the immunomodulatory effects of a-MSH are also mediated through the accumulation of cAMP.
Whether an a-MSH analog can suppress inflammatory cytokines in a LPS mouse inflammation model was examined.
This example further illustrates the ability of a-MSH to inhibit viral replication and activation.
More specifically, a-MSH or its derivatives inhibited TNF-a induced NF-kB activation and binding.
Thus, SSRIs also increase the secretion of a-MSH and its concentrations in the CNS.
The use of claim 1, wherein the anti-microbial pharmaceutical does not comprise naturally occurring a-MSH.
In another aspect, an a-MSH analogue of the invention may reduce cisplatin induced renal failure.
These are collectively referred to herein as a-MSH or Y-MSH analogues.
The neuroimmunomodulatory peptide a-MSH modulates action and production of proinflammatory cytokines including TNF-a.
The chromatogram depicting the elution of a-MSH is seen in Figure 22.
In a yet further aspect, an a-MSH analogue of the invention may reduce pulmonary vascular hypertension.
FIG . 2 is a histogram showing the affinity of IgM autoantibodies directed against a-MSH.
Figure 6 illustrates efficacy of RI a-MSH in the treatment of retinal inflammation.
Of these, a-MSH and ACTH are considered to be the main endogenous melanocortins.
Activation of MC4 receptors in the hypothalamus by a-MSH reduces appetite and increases energy expenditure.
In addition, a-MSH inhibits HIV-1 replication in acutely and chronically infected monocytes.
Figure 4 compares the anti-fungal activities of a-MSH and / or its derivatives with fluconazole.
Figure 10 illustrates the spinal cord histology of mice treated with RI a-MSH.
Figure 7 shows the effect of RI a-MSH on cAMP production in murine melanoma cells.
Recent studies have demonstrated that the anti-inflammatory actions of a-MSH are mediated by MC-1R.
Other derivatives of a-MSH are recognized for their anti-inflammatory activity.
FIG . 1 is a histogram showing the affinity of the IgG autoantibodies directed against a-MSH.
The psychotherapeutic agent, or a-MSH activity enhancer, is the antidepressant bupropion.
Figure 2 illustrates amelioration of uveitis in late-stage disease by RI a-MSH and native a-MSH.
The stimulatory effect of a-MSH in pigment cells has been known for over 50 years.
The most important endogenous agonist for central MC-4R activation appears to be the tridecapeptide a-MSH.
More particularly, such agents include dihydroxyacetone, a-MSH agonists, adenylate cyclase activators and phosphodiesterase inhibitors.
