Examples of 'abasic' in a sentence
Meaning of "abasic"
abasic (adjective) - referring to a situation or condition that is minimal, basic or essential in nature, often used in technical or scientific contexts
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- Of, pertaining to or caused by abasia.
- That has neither a purine nor a pyrimidine base.
- Missing a nucleotide base
How to use "abasic" in a sentence
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abasic
Abasic sites cause polymerases to stall.
The principle of equilibrium constitutes abasic budgetary rule.
It can be described as abasic measureof stability and performance of a society.
The result is an abasic site.
The resulting abasic sites are susceptible to hydrolytic cleavage at elevated temperatures.
Deoxyinosine can be converted to an abasic site by exposure to AlkA glycosylase.
The oligonucleotide may also comprise one or more abasic moieties.
Oligomers can also contain abasic sites and pseudonucleosides.
These abasic sites render the amplification product unamplifiable in subsequent SDAs.
Several agents are known which cleave the phosphodiester bonds in nucleic acids at abasic sites.
These abasic sites render the amplification product unamplifiable in subsequent amplification reactions.
DNA polymerase extension on these templates is terminated by abasic sites.
Abasic sites are where the DNA has molecular damage.
The position of a damaged base is called the abasic site or AP site.
This was abasic goal of the Union from the earliest days.
See also
In one embodiment the ORN further comprises at least one abasic nucleotide.
This cleavage generates abasic sites that are blocked from replication by DNA polymerase.
This releases the base from the DNA and generates an abasic site.
The resulting abasic polynucleotides are susceptible to hydrolysis and can not function as templates during PCR.
Collectively, such sites are referred to as abasic sites.
Pupil participation is abasic principle of the Curriculum Guidelines.
In an example of the disclosure, the duplex comprises an abasic nucleotide.
MetaComCo also developed ABasiC for the Amiga which was initially provided with Amigas.
An overhang containing an abasic site ; and.
MX binds to abasic AP sites and disrupts the BER pathway.
More preferably, mismatches rather than abasic nucleotides are present.
In some embodiments, an abasic nucleotide provides a stronger signal than a primary nucleotide.
In another embodiment, the spacer may be one or more abasic residues.
For this purpose, abasic nucleotides may be used.
Abasic sites were included either by incorporation of a d-spacer during oligonucleotide synthesis or deoxy uridine.
In another embodiment, spacers include one or more abasic ribose or deoxyribose moieties.
Alternatively, the abasic sites are sensitive to chemical degradation which is accelerated by elevated temperatures.
Alternatively, the second label may be linked to an abasic element of said detecting oligonucleotide.
The abasic pseudo-nucleotide lacks a base, and thus is not strictly a nucleotide.
A method according to claim 26 wherein the abasic linker is an abasic deoxyribose phosphate linker.
Abasic commonguidancedocument wasalsopre-pared and given to the different services to adapttotheir own needs.
In some embodiments, haptens are introduced on abasic phosphoramidites containing the desired detectable moieties.
In certain embodiments, terminal groups may comprise additional nucleosides and / or inverted abasic nucleosides.
Nucleotides also include ribonucleotides, deoxyribonucleotides, abasic nucleotides, inverted abasic nucleotides and nucleotide analogs.
The more abasic nucleotides the sequence have, the stronger electrical signal the sequence.
Management of your user account on the Abasic website ;.
An abasic site is also known as an apurinic / apyrimidinic or an AP site.
In PCR, the polymerases are incapable of efficiently copying templates having abasic sites.
The haptens, indicated by R, were introduced on an abasic phosphoramidite containing the desired hapten.
In addition, certain chemical bonds in DNA can undergo spontaneous hydrolysis, leading to abasic sites.
Each excises the base leaving an abasic site in a double - or single-stranded DNA.
Branching of immunostimulatory ORN can also involve the use of non-nucleotidic linkers and abasic spacers.
The process of claim 9 wherein the abasic site mimic is a tetrahydrofuran residue or D-spacer.
Cap structures include, for example, inverted deoxy abasic caps.
A represents an abasic site ; I represents inosine.
