Examples of 'activated protein c' in a sentence
Meaning of "activated protein c"
Activated protein C (APC) is a natural anticoagulant produced in the body that plays a vital role in maintaining blood flow and preventing excessive blood clotting. It is an enzyme that inhibits clotting factors in the blood, thereby reducing the risk of thrombosis. APC is often used as a medical treatment for conditions such as severe sepsis or disseminated intravascular coagulation (DIC) to help prevent blood clotting complications
How to use "activated protein c" in a sentence
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activated protein c
Treat the patient with activated protein c.
Activated protein c for use in the treatment of inflammatory skin disorders.
Neuroprotective activity of activated protein c is independent of its anticoagulant activity.
Activated protein C overwhelmingly prefers two plasma protein substrates which it hydrolyzes and irreversibly destroys.
All animal studies assessing the effects of activated protein C on microcirculation reported a beneficial effect.
Activated protein C or aPC refers to recombinant aPC.
Experimental evidence indicates that activated protein C may be clinically useful in the treatment of thrombosis.
Activated protein C is an important regulator of coagulation.
I would treat him with an activated protein C.
This purification of the activated protein C is carried out according to the method described above.
Transfected cells are assayed for the production of activated protein C.
Activated protein C helps regulate the systemic inflammatory response.
The anticoagulant activity of activated protein C was tested in several assays.
Activated protein C is a specific enzyme that inactivates procoagulant components.
It serves as a cofactor to activated protein C in the inactivation of factors Va and VIIIa.
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Activated protein C is useful in the treatment of disseminated intravascular coagulation.
The catalytic activities of activated protein C reside in the heavy chain.
Activated protein C also provides much protection of endothelial barrier function.
Cells are selected and assayed for the production of activated protein C.
Impact of different types of HRT on activated protein C resistance and haemostatic parameters.
The activated protein C formulations were analyzed for processing in a conventional freeze dryer.
The rate of reaction is dependent on the amount of activated protein C generated.
FVIII can be inactivated by activated protein C in the presence of calcium and phospholipids.
Clones of stably transfected cells are then screened for expression of activated protein C.
Activated protein C only minimally degrades the inactive precursors of these clotting factors.
Thus platelet activation contributes to reinforce the hypercoagulability due to activated protein C resistance.
Use of activated protein C for the treatment of hypercoagulable states associated with sepsis.
Activated factor Va is inactivated by activated Protein C to inhibit the coagulation process.
Activated protein C can prevent intravascular thrombosis and control the extension of existing clots.
Human recombinant activated protein C for severe sepsis.
Activated protein C also inactivates factor VIII thereby inhibiting the progress of the coagulation cascade.
Mutation in blood coagulation factor V associated with resistence to activated protein C.
It is known that activated Protein C has profibrinolytic properties.
Each chain in itself is susceptible to proteolysis by activated protein C and by Factor Xa.
APC or activated protein C whether recombinant or plasma derived.
Activated Factor VIIIa is inactivated by activated Protein C to inhibit the coagulation process.
Activated protein C anticoagulant activity is enhanced by.
During hematological investigation a protein C deficiency and resistance to activated protein C were detected.
Activated protein C is a natural anticoagulant.
A pharmaceutical composition comprising a blood coagulation factor V which is resistant against activated protein C.
Binding of activated protein C to protein S leads to a modest increase in its activity.
The change absorbance per second is proportional to pmol / ml of activated protein C.
Activated protein C resistance occurs when APC is unable to perform its functions.
Preferred bulking agents in the formulation of activated protein C are sucrose, trehalose and raffinose.
Therefore, activated protein C represents an important adjunct to in vivo fibrinolysis in man.
A composition including a therapeutically effective amount of activated protein C for use according to claim 1.
Activated protein C and hospital mortality in septic shock, a propensity-matched analysis.
This invention relates to enzymology, particularly to methods for preventing degradation of activated protein C.
A method for producing activated protein C comprising,.
The fraction thereby obtained is placed on aprotinin-Sepharose in order to purify the activated protein C.
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