Examples of 'activation of nf-kb' in a sentence

Meaning of "activation of nf-kb"

Activation of nf-kb: This phrase pertains to the process of initiating or triggering the activation of the NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) protein. NF-kB is a crucial transcription factor involved in various cellular processes, including immune responses, inflammation, and cell growth and survival

How to use "activation of nf-kb" in a sentence

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activation of nf-kb
A TNFa signaling pathway can comprise activation of NF-kB.
The activation of NF-kB has been implicated in a large number of human diseases.
This will result in the activation of NF-kB.
Activation of NF-kB increases expression of a number of genes that mediate inflammation.
In contrast to the previous experiment, reduced activation of NF-kB was observed.
Chronic activation of NF-kB frequently associated with inflammatory disorders and cancer.
Disease states characterized by undesired activation of NF-kB.
Activation of NF-kB would further activate the expression of inflammation-associated genes.
Such ubiquitination results in the release and activation of NF-kB.
Increased activation of NF-kB is associated with a range of inflammatory diseases and autoimmune conditions.
In other embodiments, the formulations are for use in inhibiting the activation of NF-kB.
However, a compound that inhibits the activation of NF-kB have not been known yet.
Inhibitors of activation of NF-kB include caffeic acid phenethyl ester and preparations of bee propolis.
Even more preferably, the cellular process comprise activation of NF-kB gene transcription.
LPS-induced activation of NF-kB and JNK appears to be independent of the presence of MyD88.

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Such compounds are particularly useful for treating diseases in which activation of NF-kB is implicated.
The effects of D1 on the activation of NF-kB in macrophages were therefore investigated.
This revealed that the compounds of the present invention specifically inhibit the activation of NF-kB.
HTB markedly inhibits the activation of NF-kB induced by LPS in human PBMCs.
Previous studies have implicated kinases other than MEKK1 in the activation of NF-kB.
A kinase critical to the activation of NF-kB is the IkB kinase ( IKK ).
The degradation of IkB-a is a prerequisite for the activation of NF-kB.
Activation of NF-kB can comprise recruitment of proteins TRAF2 and RIP.
Even more preferably, the cellular process comprises activation of NF-kB gene transcription.
This condition causes increased degradation of Ik-Ba, thereby resulting in the activation of NF-kB.
Abstract, T. gondii interferes with the activation of NF-kB signaling pathways.
The IkB kinases ( IKKs ), are key regulatory signaling molecules coordinating the activation of NF-kB.
An exemplary TLR3 activation results in activation of NF-kB in response to the TLR3 ligand.
Of interest, the cellular response to ara-C also includes activation of NF-kB.
In rheumatoid arthritis ( RA ), the activation of NF-kB in synovium has been observed.
The protein of Claim 9, wherein said activity is activation of NF-kB.
Example 2, Inhibition of the activation of NF-kB induced bv immune complexes ( IC ) in rat macrophages.
This in-vivo study measured the regulation and activation of NF-kB in mice.
Example 1, Inhibition of the activation of NF-kB induced by TNF-a in HUVEC.
Figure 4 illustrates the inhibitory effect of I-TRAF on activation of NF-kB.
Under these conditions cYc enhances the activation of NF-kB induced by NIK.
These results suggest that MEKK1 plays a role in TNF-a activation of NF-kB.
The method of claim 5, wherein the cellular process comprises activation of NF-kB gene transcription.
When expressed alone, SIVA1 and SIVA2 caused only slight activation of NF-kB.
An exemplary ST2L biological activity results in activation of NF-kB in response to IL-33.

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