Examples of 'active ester' in a sentence
Meaning of "active ester"
Active ester: a reactive chemical compound containing an ester group that is capable of undergoing specific chemical reactions
How to use "active ester" in a sentence
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active ester
Derivatisation to active ester was then performed as follows.
There are various kinds of active ester.
Preferably the active ester of the structure.
The methamphetamine derivative is converted to its active ester.
The active ester solution was used in later examples.
Preparation of the active ester.
The active ester group is preferable.
Other carboxy protecting groups are pharmaceutically active ester forming groups.
The active ester was precipitated with dry ether.
Derivatisation to active ester.
Unreacted active ester groups were quenched with ethanolamine.
Another carboxy protecting group is a pharmaceutically active ester forming group.
This solution of active ester was used in later examples below.
Another method of forming conjugates is through the use of active ester intermediates.
The purified active ester fractions were pooled and concentrated to dryness.
See also
Insoluble substances were filtered off by celite to obtain a dichloromethane solution of the active ester.
Active ester derivatives are well known to those skilled in the art.
The acid derivative was converted to an active ester and then conjugated to a protein.
An active ester can include a carboxyl group linked to an active leaving goup.
To this stirred mixture was added the mixture of the side chain active ester.
The active ester solution was filtered and added to the protein solution.
The reaction mixture was then stirred overnight at room temperature to produce an active ester.
Active ester derivatives arc well known to those skilled in the art.
Wherein Ra represents an active ester of a carboxylic acid.
The active ester is then reacted with the antigen to give the conjugate.
Each amino acid was converted to the Hobt active ester.
Adding imidazole to said active ester for the formation of an active phosphoramidate.
Insoluble substances were filtered off by celite to obtain a DMF solution of the active ester.
This bis active ester would then be conjugated to a linker modified cyclic compound.
PEGylation by acylation generally involves reacting an active ester derivative of polyethylene glycol.
That active ester reacts with amino groups to form topiramate analog conjugates.
Each coupling is mediated with diisopropyl carbodiimide with HOBT to form the active ester.
The active ester was dried to an oil and triturated with anhydrous ethyl ether.
PEGylation by acylation generally involves reacting an active ester derivative of PEG.
The active ester is then reacted with the lipophilic molecule to give the conjugate.
The amine is reacted with Sulfo EGS to form an active ester NHS group.
The structure of the active ester also significantly affected the directionality of the conjugation reaction.
For example, a targeting moiety may contain an active ester or a maleimide group.
The active ester XIIIa is then reacted with polypeptide to yield amide bond conjugate XVII.
In some cases, this active ester is isolated before use.
The active ester according to claim 1, wherein said alcohol is an aromatic alcohol.
After filtration, the filtrate was evaporated in vacuo to give active ester as an oil.
Coupling the active ester to the free amine of cystamine ;.
The reactive derivative includes a halide, anhydride, an active ester of a corresponding acid.
The active ester according to claim 1, wherein said glycosaminoglycan is hyaluronic acid.
A method of preparing a succinimidyl carbonate active ester of a branched non-antigenic polymer comprising,.
The active ester is isolated, generally as a solid, and stored under dry conditions.
The solvent was removed by distillation under reduced pressure, which gave an active ester compound.
The method for producing active ester of Z-Trp-OH can be a similar manner as above.
Indomethacin-ethanolamide and indomethacin-glycine ethanolamide derivatives were synthesised vía the active ester chemistry and palmitoylated.
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