Examples of 'active metabolite' in a sentence

Meaning of "active metabolite"

active metabolite: An 'active metabolite' refers to a substance that is produced when a drug is metabolized in the body and has pharmacological effects. It is the metabolically active form of a drug that contributes to its therapeutic or physiological actions

How to use "active metabolite" in a sentence

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active metabolite
Desloratadine is the primary active metabolite of loratadine.
It is an active metabolite of allopurinol and it is cleared renally.
Nortilidine is the major active metabolite of tilidine.
The active metabolite of diacerein is monoacetylrhein or rhein.
Rhein is the major active metabolite of diacerein.
The active metabolite is eliminated entirely by renal excretion.
Be aware that this amounts to an active metabolite.
The active metabolite is not observed.
That formed the active metabolite.
Active metabolite monohydroxycarbazepine was not assessed.
Paliperidone is the active metabolite of risperidone.
Active metabolite of a thrombin receptor antagonist.
Enalaprilat is the active metabolite of enalapril.
It does not require metabolic conversion to an active metabolite.
Spiraprilat is the active metabolite of spirapril.

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The active metabolite is further metabolised to two inactive compounds by.
Quinaprilat is the active metabolite of quinapril.
There was also a trend to lower exposure to the active metabolite.
No pharmacologically active metabolite has been found.
Oxidative depropylation of the sulfamide yields a pharmacologically active metabolite.
Equol is an active metabolite of soybean isoflavone.
Desfuroylceftiofur is the principal active metabolite.
Paliperidone is an active metabolite of risperidone.
Blockage of platelet aggregation by clopidogrel is entirely due to an active metabolite.
Because the clarithromycin active metabolite has reduced activity.
The active metabolite is formed in hepatocytes and not observed in plasma.
Parecoxib is rapidly hydrolysed to the active metabolite valdecoxib.
The pharmacologically active metabolite responsible for efficacy is fingolimod phosphate.
It is a prodrug and is converted to the active metabolite hycanthone.
The major active metabolite was not evaluated for genotoxic potential.
Macitentan and its active metabolite.
It is an active metabolite of loratadine.
Amphetamine can arise as a pharmacologically active metabolite of methamphetamine.
It is an active metabolite of etozoline.
It produces amphetamine as an active metabolite.
Flutamide and its active metabolite were not well dialyzed.
Molsidomine is metabolized in the liver to the active metabolite linsidomine.
Selexipag and its active metabolite do not inhibit transport proteins.
Fexofenadine is the predominant human and animal active metabolite of terfenadine.
It is an active metabolite of clomifene.
Tapentadol exerts its analgesic effects without a pharmacologically active metabolite.
Measure its active metabolite.
Rifampicin and fluconazole have been reported to reduce levels of active metabolite.
Norverapamil is an active metabolite of verapamil.
Associated with a decrease in corresponding values for the active metabolite.
Fesoterodine active metabolite.
Selexipag is rapidly absorbed and is hydrolysed by carboxylesterases to its active metabolite.
A prodrug moiety may include an active metabolite or drug itself.
The major active metabolite was not evaluated for genetic toxicity potential.
It is unknown whether oseltamivir or its active metabolite are excreted in human milk.

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Examples of using Metabolite
The major metabolite of vortioxetine is pharmacologically inactive
Homocysteine is a key junction metabolite in methionine metabolism
The main metabolite is characterised as toltrazuril sulfone
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Examples of using Active
She had active orthodontic treatment as a teenager
Integral person member active in his environment
It has active community support and acceptance
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