Examples of 'adenovirus vectors' in a sentence
Meaning of "adenovirus vectors"
adenovirus vectors - a type of gene delivery system often used in genetic research and therapy
How to use "adenovirus vectors" in a sentence
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adenovirus vectors
A number of adenovirus vectors are known in the art.
In particularly preferred embodiments adenovirus vectors are used.
A number of adenovirus vectors have also been described.
Other viral vectors of use are herpes virus or adenovirus vectors.
Adenovirus vectors may originate from human adenovirus.
A number of adenovirus vectors are known.
Adenovirus vectors can be produced in large quantities in a relatively simple system.
Preferred are adenovirus vectors.
The adenovirus vectors of the invention are typically replication defective.
This packaging system will be used to produce minimal adenovirus vectors.
Novel adenovirus vectors.
The overlapping sequences were deleted from the new adenovirus vectors.
The adenovirus vectors useful in the invention are typically replication deficient.
Seroconversion to the serotype of the adenovirus vectors employed was determined by neutralization assays.
Adenovirus vectors with modified tropism for the treatment of colorectal cancer.
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Seroconversion to the serotype of the adenovirus vectors employed was determined by neutralization test procedures.
Adenovirus vectors are derived from nuclear replicating viruses and can be defective.
I initially evaluated the transduction efficiency and transgene expression of the adenovirus vectors.
The adenovirus vectors useful in the present disclosure are typically replication defective.
Particle aggregation is a significant and not fully resolved issue for adenovirus vectors as well.
Adenovirus vectors have been used in eukaryotic gene expression and vaccine development.
The invention further provides immunogenic compositions comprising the isolated adenovirus vectors of the invention.
Adenovirus vectors of the invention comprise an OriP sequence and adenovirus genome sequences.
There is controversy about the mechanism by which First Generation adenovirus vectors are potent immunogens.
Adenovirus vectors can be purified and formulated using techniques known in the art.
EXPERIMENTAL Generation of cell lines able to transcomplement El defective recombinant adenovirus vectors.
Treatments based on adenovirus vectors should not have negative effects on tumor progression or metastases.
In a preferred embodiment, adenovirus vectors are used.
Adenovirus vectors and methods for their construction have been described e . g.
For example, adenovirus vectors are used.
A technology based on the development and production of adenovirus vectors ( gene carriers ).
Further advantages of adenovirus vectors over retroviruses include the higher levels of gene expression.
The advantages of minimal adenovirus vectors e . g.
Accordingly, adenovirus vectors have been developed which make use of these advantages.
The present invention also encompasses combinations of vectors, in particular adenovirus vectors.
The newly developed adenovirus vectors harbouring an El deletion of nt.
Preferred vector types include poxvirus vectors, adenovirus vectors and plasmids.
In other embodiments, the adenovirus vectors can be administered for post-exposure prophylactics.
For example, vaccinia virus is more potent in replication and spread than adenovirus vectors.
In some embodiments, adenovirus vectors are used.
Moreover, adenovirus vectors have already been applied for clinical gene-therapy trials.
In alternate embodiments, such gutted adenovirus vectors may be an aspect of the invention.
Thus, adenovirus vectors strongly stimulate innate immune responses followed by an adaptive immune response.
Specific tumor-cell killing with adenovirus vectors containing the apoptin gene.
Thus, a need exists for a chromatographic method for purifying viral vectors such as adenovirus vectors.
In certain embodiments, the adenovirus vectors are used to generate an immune response against a cancer.
Hence, the process of the invention is suitable for recombinant adenovirus vectors of different serotypes.
Once inside the cell, adenovirus vectors rarely integrate into the host chromosome.
Suitable adenoviral vectors thus include Ad5 vectors and simian adenovirus vectors.
Replication-defective adenovirus vectors by contrast remain episomal and therefore allow transient expression.
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