Examples of 'adp-ribose' in a sentence
Meaning of "adp-ribose"
adp-ribose (verb) - The act of adding ADP-ribose molecules to proteins, often as a post-translational modification to regulate their function or structure within a cell
Show more definitions
- A phosphate ester of ribose and adenosine diphosphate
How to use "adp-ribose" in a sentence
Basic
Advanced
adp-ribose
The potency of ADP-ribose as a glycating agent is known.
The chemistry of the glycation reactions by ADP-ribose is unique.
The enzyme transfers NAD to the ADP-ribose polymer, binding it onto a number of proteins.
Many different amino acid side chains have been described as ADP-ribose acceptors.
Histone H1 and ADP-ribose are known to interact, leading to formation of a fluorescent product.
Synthesis and degradation of cyclic ADP-ribose by NAD glycohydrolases.
PARP and PARG form a cycle that converts a large amount of NAD to ADP-ribose.
The toxins catalyse the transfer of an ADP-ribose unit from NAD+ to a target protein.
The overactivation of PARP may lead to rapid consumption of NAD+ to form ADP-ribose polymers.
The first pair of wells contained the reactants ADP-ribose and histone H1, without any potential inhibitors.
Figure 3 presents the chemistry of glycation reactions vía ADP-ribose.
The examples described herein show the potency of ADP-ribose in causing histone H1 carbonylation.
Earlier studies have focused on a pathway that involves the intranuclear generation of ADP-ribose ( ADPR ).
ADP-ribose caused extensive carbonylation, while D-ribose caused a lesser amount.
As a preliminary assay for NAD-glycohydrolase activity, agmatine was used as an ADP-ribose acceptor.
See also
Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.
Figure 7 shows that aminoguanidine suppresses the glycation of histone H1 by ADP-ribose.
The coenzyme NAD+ is also consumed in ADP-ribose transfer reactions.
NAD+ is required as substrate for generating ADP-ribose monomers.
Figure 5 compares glucose, ribose, ADP-glucose, and ADP-ribose in the method of the invention.
As with mono-ADP ribosylation, the source of ADP-ribose is NAD.
ADP-ribosylation is the addition of one or more ADP-ribose moieties to a protein.
The coenzyme NAD+ can also be consumed by in ADP-ribose transfer reactions.
