Examples of 'afatinib' in a sentence
Meaning of "afatinib"
afatinib (noun): 'Afatinib' is a medication used in the treatment of certain types of cancer, particularly non-small cell lung cancer
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- A drug against non-small cell lung carcinoma.
How to use "afatinib" in a sentence
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afatinib
Giotrif contains the active substance afatinib.
Refer to the afatinib SmPC for dosage adjustment.
Monitor for ADRs related to afatinib.
Refer to the afatinib SmPC for.
Important considerations for taking afatinib.
Afatinib is designed to block tumor cell growth in several ways.
Preferred examples of such drug include afatinib or dacometinib.
Afatinib for lung cancer.
It has never been directly compared with afatinib.
Afatinib is the dimaleate salt.
Covalent adducts to proteins were the major circulating metabolites of afatinib.
How afatinib works.
The active substance is afatinib.
This is because the amount of afatinib in your body may be decreased.
Fertility studies in humans have not been performed with afatinib.
See also
Administering afatinib with.
Afatinib may shrink the cancer or stop it growing for some time.
Food effect on afatinib.
Afatinib is not an inhibitor or an inducer of CYP enzymes.
Refer to the afatinib.
Afatinib targets certain proteins called EGF receptors within NSCLC cells.
You may need to stop taking afatinib for a short time.
GIOTRIF is a medicine which contains the active substance afatinib.
In vitro studies indicated that afatinib is a substrate and an inhibitor of the transporter BCRP.
Side effects of afatinib.
Afatinib is eliminated mainly by biliary / faecal excretion.
The trial was not able to demonstrate that afatinib improves survival.
Erlotinib, gefitinib and afatinib inhibit tyrosine kinase at the epidermal growth factor receptor.
Caution should be exercised in administering afatinib with Kaletra.
I would consider afatinib for patients with brain metastases, rather than other EGFR TKIs.
Lung cancer cells with mutated EGFR proteins are particularly sensitive to afatinib.
Caution should be exercised in administering afatinib with Norvir refer to the afatinib SmPC.
Boehringer Ingelheim and QIAGEN are partnering on a companion diagnostic for afatinib.
Uses of Afatinib.
Enzyme-catalyzed metabolic reactions play a negligible role for afatinib in vivo.
Based on this, it is likely that afatinib is excreted in human milk.
Diarrhea, Diarrhea is a common side effect of afatinib.
If indicated, elimination of unabsorbed afatinib may be achieved by emesis or gastric lavage.
What GIOTRIF contains - The active substance is afatinib.
The embryo-foetal development studies performed on afatinib revealed no indication of teratogenicity.
Afatinib is a potent and selective, irreversible ErbB Family Blocker.
ADRs related to afatinib.
Hypersensitivity to afatinib or to any of the excipients listed in section 6.1.
Anticancer agents Afatinib.
In vitro binding of afatinib to human plasma proteins is approximately 95.
According to the invention, the EGFR inhibitor is afatinib or dacomitinib.
Afatinib is eliminated with an effective half-life of approximately 37 hours.
Caution should be exercised in administering afatinib with ritonavir ( refer to the afatinib SmPC ).
In some embodiments, the pan-ErbB inhibitor is afatinib.
Cross-trial comparisons indicate that afatinib provides the longest progression-free survival.
