Examples of 'affinity constants' in a sentence
Meaning of "affinity constants"
affinity constants: in chemistry, these are values that represent the strength of interaction between molecules
How to use "affinity constants" in a sentence
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affinity constants
Affinity constants may be determined using well known techniques.
Antibodies are assessed by affinity constants.
The affinity constants are decreasing from the bottom to the top.
With this method it is possible to measure binding kinetics as well as affinity constants.
Affinity constants at equilibrium of the three MAb for the four analogues.
Those which have the higher affinity constants for the target are most likely to bind.
Affinity constants are a measure of the interaction between a particular ligand and its cognate receptor.
These figures then allow calculation of the Association and Dissociation Affinity Constants.
Kinetic and affinity constants measured by Biacore.
The BIAevaluation ™ software was used to fit the curves and calculate the affinity constants.
Determination of the affinity constants of labeled Mabs were done according to Hellman et al.
More desirable for ligands are substances with affinity constants of about 10 µm or less.
The relative affinity constants of the humanized antibodies Fig.
From the sensograms, the kon and koff constants and the affinity constants KD were calculated.
Affinity constants were calculated from the data by Scatchard analysis.
See also
Preferably, higher affinity constants are applied.
The affinity constants are calculated by means of a bivalent analyte method Karlsson et al.
From the results, the affinity constants were calculated,.
Affinity constants are determined in accordance with the appropriate method described in Holvoet et al.
Example 12 exemplifies a method for determining affinity constants of anti-ErbB2 monoclonal antibodies by flow cytometry.
Affinity constants are expressed in units of reciprocal molarity i . e.
Figure 7c is an histogram illustrating the affinity constants ( KD ) of the humanized antibodies.
Affinity constants are affected by temperature, pH and solvent.
Example 10 exemplifies a method for determining affinity constants of anti-MIF antibodies by BIACORE technology.
Affinity constants of MAbs are listed in table 2.
A 1:1 Langmuir model was assumed and apparent kinetic constants and also affinity constants were calculated.
Kinetic and affinity constants are provided in the Table 2 below.
See Examples 1-3, below for more information about determining affinity constants for the humanized antibodies.
Affinity constants were determined as described above, with the results shown in Table 5.
As before, kinetic parameters and steady-state affinity constants were determined from the sensorgrams ( Table 3 ).
The affinity constants may be determined according to the method as described in Example 1.
This is reflected in the affinity constants ( Figure 7c ).
Rate and affinity constants for monoclonal antibodies that bind to human CD4.
Values for dissociation affinity constants ( KD ) were determined from duplicate experiments.
The affinity constants Ki were calculated using the equation of Horowitz et al, Proc.
The off-rates and affinity constants are shown in Table B-1.
Affinity constants ( KD ) were calculated applying a 1:1 interaction model using the ForteBio Data Analysis software.
Table V, below, shows affinity constants of XenoMouse-derived antigen-specific fully human Mabs.
Affinity constants were measured by competition binding to hGHbp versus 125I-labeled hGH.
Kinetic and affinity constants of antibody 1 E4 for human and cynomolgus RANTES measured by Biacore.
Kinetic and affinity constants were determined using the Biaevaluation software with a 1:1 interaction model / global fit.
Those having affinity constants of at least 10 ¹ ⁰ M ⁻ ¹ are generally taken forward for cloning.
Kinetic and affinity constants were determined using Biaevaluation software ( Biacore ) with a 1:1 interaction model / global fit.
Table 6, Affinity constants of RF1 binding to HBsAg.
The affinity constants ( Kd ) are shown in Table 2.
Their affinity constants for native LDL, MDA-modified LDL, and OxLDL are as follows,.
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