Examples of 'agrin' in a sentence
Meaning of "agrin"
Agrin is a noun referring to a protein that is important for the formation and maintenance of the neuromuscular junction
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- grinning; having happiness or satisfaction apparent on one's face
- a protein involved in the formation of neuromuscular junctions during embryonic development
How to use "agrin" in a sentence
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agrin
Agrin today is a strange day for me.
Neurotrypsin cleaves agrin at two sites.
Agrin exists in several isoforms and splice variants.
Later bleeds all had agrin antibodies in the serum.
Agrin exists in several isoforms.
The transfected muscles produced and secreted agrin protein.
Cleavage of agrin by neurotrypsin contributes to neuromuscular plasticity and remodelling.
Hengov grieves on the cliff from where Agrin jumped to her death.
A Alignment of agrin sequences of different species.
It is activated by a nerve-derived proteoglycan called agrin.
At present, agrin is the only known target of neurotrypsin.
Pericellular HSPGs include mainly perlecan, agrin.
Agrin appears to be present in a number of isoforms, which result from alternative mRNA splicing.
Also, ennui is very important for agrin function.
Agrin is the nerve-derived factor that initiates the formation of the neuromuscular synapses.
See also
Motor neurons express predominantly y4 agrin.
For example, agrin was first isolated from Torpedo.
No peptide located outside of the margins of the 22kDa fragment of agrin was found.
AndI ' mgonnacutyou agrin down here on your neck.
In one embodiment, rabbits were transfected with a plasmid containing the cDNA for rat agrin.
Agrin and LRP4 antibodies as new biomarkers of myasthenia gravis.
Nineteen days post-transfection, rabbit serum contained significant antibodies against rat agrin.
Nate Agrin and Ken-ichi Ueda continued work on the site with Sean McGregor, a web developer.
B-Actin was probed on the stripped membrane of the agrin immunoblot.
Hence the 22-kDa fragment of agrin induces an increase in filopodia number in neurotrypsin-deficient mice.
Purification vÃa an antibody raised against the C-terminal part of agrin can also be used.
The 22-kDa fragment of agrin can be used for diagnosing the disturbances or diseases mentioned.
The mutation K to A in the B-cleavage site efficiently abolishes a cleavage of the agrin fragment.
AndI ' mgonnacutyou agrin down here on your neck . It 's gonna run clear across to there.
Fig . 3 shows domain structure of transmembrane agrin.
The sequence of the 22-kDa fragment of agrin is shown in bold types.
Fig . 1 shows a schematic representation of agrin.
Similar results were obtained for the 22-kDa agrin fragment except for the lung.
Fig . 1, shows schematic representation of the domain structure of agrin.
Upper panel, Transfection of agrin alone resulted in a signal above 250 kDa in the cell lysate.
Fig . 4 shows that neurotrypsin cleaves agrin in vivo.
Agrin was first identified by the U.J. McMahan laboratory, Stanford University.
In these tissues we also found the 90-kDa cleavage product of agrin.
Bassat, E. et al. The extracellular matrix protein agrin promotes heart regeneration in mice.
This indicates that the 22-Da fragment is indeed the result of neurotrypsin-dependent cleavage of agrin.
In neurotrypsin-deficient mice no agrin immunoreactivity was detectable at 22 kDa or 90 kDa.
Fig . 2B shows how neurotrypsin cleaves agrin in vitro.
Agrin has a core protein mass of approximately 225 kDa.
Peptide 1 starts at the neurotrypsin-dependent B cleavage site of agrin.
Note that the 22-kDa fragment of agrin is only detected in the wild-type mouse.
A small globular motif ( L B ) in the coiled-coil domain of the B chains binds to agrin.
Recombinant 22-kDa fragment of agrin is produced as described in Example 7.
Both were localized to the 22-kDa fragment of agrin.
The 22-kDa fragment ranges from the B-cleavage site to the C-terminus of agrin.
