Examples of 'alpha toxin' in a sentence
Meaning of "alpha toxin"
alpha toxin: a poisonous substance that is highly potent or harmful
How to use "alpha toxin" in a sentence
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alpha toxin
Alpha toxin is a highly toxic substance and is haemolytic.
Antibodies to staphylococcal alpha toxin were separated into two distinct populations.
Alpha toxin is believed to be a key virulence determinant in staphylococcal pneumonia.
One population prevented binding of alpha toxin onto erythrocyte membranes.
The alpha toxin polypeptides sometimes are referred to as alpha hemolysin.
Cartoon representation of the modeled structure of a soluble monomer of alpha toxin.
Alpha toxin also has a powerful action on vascular smooth muscle.
The phenotypic linkage to functionality for alpha toxin is the demonstration of haemolytic activity.
Alpha toxin pore formation often leads to cell dysfunction or lysis.
Aureus cells expressing and secreting alpha toxin can also be used to generate antibodies.
These three regions represent two different locations in the three dimensional structure of alpha toxin.
Other forms of alpha toxin useful for generating antibodies also can be used.
This toxin is hemolytic, but not as hemolytic as alpha toxin.
Alternatively the alpha toxin is chemically detoxified by treatment with a cross-linking reagent, formaldehyde or glutaraldehyde.
Human platelets, endothelial cells and mononuclear cells are susceptible to the effects of alpha toxin.
See also
In contrast, native alpha toxin from Clostridium septicum comprises only a large lobe binding domain.
Figure 21 depicts cartoon representations of alpha toxin structures.
The an anti-alpha toxin antibody or fragment may deplete alpha toxin secreted by pathogenic S. aureus.
Purification of native alpha toxin from S. aureus.
The alpha toxin of C. septicum or any immunogenic fragment.
Figure 20 shows sequence alignments of alpha toxin and LukF-PV proteins.
The alpha toxin of C. novyi or any immunogenic fragment.
Figure 3 - Purification of alpha toxin under native conditions.
Alpha toxin has a subunit molecular weight of about 33 kDa.
The underlined, shaded sequence is the N-terminus of the mature C. septicum alpha toxin.
Alpha toxin and aerolysin share approximately 72 % sequence similarity and have numerous functional similarities as well.
Absent the C-terminal cleavage the C. septicum alpha toxin is not functional.
Notably, C. septicum alpha toxin does possess haemolytic activity Ballard et al.
Native alpha toxin ( nAT ) was purified from the S. aureus Wood strain.
The CLH putative alpha toxin has a Glutamine residue instead of Arginine in the analogous R398 position.
Since alpha toxin is a very stable protein That et al ., J. Biol.
