Examples of 'alpha-synuclein' in a sentence
Meaning of "alpha-synuclein"
alpha-synuclein (noun) - a protein found in the human brain, particularly in the neurons. It is associated with various neurodegenerative disorders, including Parkinson's disease, and is the primary component of Lewy bodies, which are pathological protein aggregates
How to use "alpha-synuclein" in a sentence
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alpha-synuclein
Alpha-synuclein is found throughout the brain.
The aggregation mechanism of alpha-synuclein is uncertain.
Alpha-synuclein is a protein found in the human brain.
Preclinical research also targets alpha-synuclein.
Aggregated alpha-synuclein in the neurons of the appendix.
Humanized antibodies that recognize alpha-synuclein.
Doubling of alpha-synuclein production due to gene duplication.
These diseases are characterized by aggregations of alpha-synuclein.
Alpha-synuclein is a protein which is mainly found intraneuronally.
Immunization of human alpha-synuclein tg mice.
Alpha-synuclein is predominately degraded by lysosomes.
These clumps are made of a protein caled alpha-synuclein.
Alpha-synuclein binds only to curved and negative membranes.
Inhibiting formation and toxicity of alpha-synuclein aggregates.
Aggregated alpha-Synuclein is visible in the neurons of the appendix.
See also
The main constituent is a protein called alpha-synuclein.
They are based on detection of alpha-synuclein in the skin or intestines.
Lewy bodies are primarily comprised of a protein called alpha-synuclein.
Alpha-synuclein is a type of protein naturally found in the human body.
This is a truncated form of alpha-synuclein.
Toxic aggregates of alpha-synuclein accumulate and are not efficiently cleared.
For more information go to Alpha-Synuclein.
Toxic heaps of alpha-synuclein accumulate and are never taken away.
Lewy bodies consist mainly of a protein called alpha-synuclein.
The reduction of alpha-synuclein is particularly beneficial in the treatment of synucleopathies.
These GCIs accumulate a specific protein known as alpha-synuclein.
Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.
Several different moieties may be used to label alpha-synuclein.
These alpha-synuclein expression plasmids were transformed to appropriate yeast strains.
Curcumin inhibits overproduction of alpha-synuclein and prevents its mutations.
The protein encoded by this gene is highly homologous to alpha-synuclein.
Apparently, alpha-synuclein is essential for normal development of the cognitive functions.
The ratio of labeled to unlabeled alpha-synuclein was calculated for each sample.
Alpha-synuclein is a protein that is normally present in the neurons of the brain.
The protein whose in vivo concentration may be measured may be alpha-synuclein.
At every residue at which alpha-synuclein binds to a membrane, the rotation slows down.
The expression levels were found similar between the alpha-synuclein derivatives.
To study alpha-synuclein further, the researchers put the protein in fruit flies.
Several neurodegenerative disorders are caused by aggregates of a single protein known as alpha-synuclein.
It has not been clear until now what alpha-synuclein actually does in the cell.
Alpha-synuclein is physiologically excreted by enteric neurons into the lumen of the intestine.
This apparent hardiness made alpha-synuclein easy to work with in the lab.
The human brain contains large quantities of the small alpha-synuclein protein.
Strategies targeting alpha-synuclein might be a possibility to address this unmet medical need.
Studies have also suggested a possible antioxidant activity of alpha-synuclein in the membrane.
Oligomeric alpha-synuclein is linked with the death of cells in the nervous system.
The antibodies can also be used in detecting fragments of alpha-synuclein as described above.
In another embodiment, alpha-synuclein may be isolated or purified by affinity chromatography or immunoaffinity chromatography.
Optionally, the transgenic nonhuman animal comprises a transgene expressing human alpha-synuclein.
Collection of alpha-synuclein from the cells and a corresponding normal sample in vitro ;.
