Examples of 'amide coupling' in a sentence
Meaning of "amide coupling"
amide coupling: In organic chemistry, amide coupling refers to a chemical reaction in which an amide bond is formed between an amine and a carboxylic acid, often catalyzed by coupling agents or activating reagents
How to use "amide coupling" in a sentence
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amide coupling
Representative procedure for amide coupling reaction.
Amide coupling is carried out using standard literature conditions.
They are bonded together using an amide coupling reaction.
Standard amide coupling conditions are used for this reaction.
The crude acid was subjected to the subsequent amide coupling without further purification.
Other suitable amide coupling reagents and conditions are known in the field.
Procedures have been developed which use reagents such as carbodiimides as amide coupling agents.
Use material crude in the amide coupling without further purification.
Amide coupling may be performed using any of a number of common peptide coupling reagents.
This was used in the subsequent amide coupling without further purification.
Typical amide coupling methodology could be used to prepare amides from acids.
The coupling reaction can proceed using any suitable amide coupling reagent.
Additional amide coupling reagents also include uronium and phosphonium based reagents.
The group A can also be a carboxylic acid for use in standard amide coupling reactions.
Amide coupling may be carried out in presence of trialkyl aluminium Chem.
See also
The reaction of Scheme J is typically conducted under amide coupling conditions known in the art.
An amide coupling reaction with a carboxylic acid leads to the formation of intermediates 6.
General procedure 3 for an amide coupling.
Other amide coupling additives, such as HOAt can also be used to enhance the reaction.
The reaction conditions for the amide coupling are in a solvent e . g.
Total amount of 11 novel bromotyramine derivatives were synthesized by amide coupling.
In another embodiment, the amide coupling agent is TCTU.
The aqueous amide coupling was carried out or 20 minutes at ambient temperature.
Procedure for the preparation of mannosides vÃa amide coupling reaction,.
Reactions successfully performed include amide coupling and sequential copper-catalysed Huisgen cycloaddition.
In some embodiments, the coupling conditions comprise an amide coupling reagent.
Method 9, General procedure for amide coupling using excess acid chloride followed by treatment with ammonia.
When Q is an amide group, the reaction can be performed under conventional amide coupling conditions.
In some embodiments, the amide coupling partner is independently selected from CDI, TBTU or TCTU.
DMF and stirred at rt for 1-2 h until completion of the amide coupling.
A general procedure for HATU amide coupling is shown below,.
Using standard amide coupling techniques as described above, 59 was converted to the title compound.
In yet another embodiment, the amide coupling partner is CDI.
Subsequent amide coupling as described in Scheme 1 affords macrocycles 24.
In one or more embodiments, the amide coupling partner is TCTU.
A variety of amide coupling reagents such as EDC, PyBrop, etc . are commercially available.
A hydrolysis leads to a compound of type D, then an amide coupling leads to a compound of type E.
Any elaboration of X and / or Z is, however, usually carried out prior to ester or amide coupling.
In yet another embodiment, the amide coupling agent is independently selected from TBTU or TCTU.
Reacting compound of formula Iaa-1 with a suitable acid under suitable amide coupling conditions ;.
Coupling of this with 7 under normal amide coupling conditions followed by de-protection provides 28.
For example, when PG = acetyl, the reaction can be performed using known amide coupling methodologies.
Ester hydrolysis followed by amide coupling of the resulting acid with N, O-dimethylhydroxylamine yields the amide 66.
Precursors T, AJ or AV might be submitted to an amide coupling ( Scheme 21 ).
Amide coupling product 10 is obtained.
Derivatives ( I-1 ) are prepared using the amide coupling as described in the general scheme A.
Typically, an amide coupling reagent and a catalyst such as N, N - dimethylaminopyridine ( DMAP ) are used.
General procedure: Amide coupling sequence:.
General procedure, Amide coupling / Boc deprotection sequence,.
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