Examples of 'amide formation' in a sentence
Meaning of "amide formation"
Amide formation: A chemical reaction in which an amide is formed by the combination of an amine with a carbonyl group, typically an acid chloride or acid anhydride
How to use "amide formation" in a sentence
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amide formation
Solution phase amide formation using PyCloP.
Amide formation may then be the final step.
Typical methods for amide formation can be used.
Amide formation using a coupling reagent.
Typical methods for amide formation can be applied here.
Amide formation reactions are well known in the synthetic art.
General procedure for amide formation from a carboxylic acid.
Amide formation using a suitable carbodiimide is an additional illustrative standard method.
General procedure for amide formation from an activated ester derivative.
The reaction can be effected according to known amide formation methods.
Standard amide formation gave the versatile bromo intermediate.
Only primary and secondary amines can undergo amide formation.
The reaction proceeds via a first amide formation step followed by cyclisation.
The chemical literature is extensive regarding methods for amide formation.
The amide formation reaction may occur in the presence of a base in a solvent.
See also
A tertiary amine hydrochloride is preferably employed to avoid the risk of amide formation.
The reaction proceeds by a first stage of amide formation followed by ring formation.
One group of linking group reagents will involve carboxyl groups resulting in amide formation.
In particular this amide formation step may be performed under high dilution conditions.
Water distilled from the reaction mixtures as the amide formation reaction proceeded.
Amide formation followed by hydrolysis of ester affords the compounds Im.
Such reactions would include esterification or amide formation using methods well known in the art.
In the final embodiment the reaction between resin and bridging molecule occurs through amide formation.
Hydrolysis of esters followed by amide formation affords the resulting compound Iv.
Amide formation using a coupling reagent and acid mediated tert - butylcarbamate deprotection.
The TPP activates the carboxylic acid group to achieve amide formation with the diamine.
Generally, amide formation can be accomplished vÃa conventional synthetic techniques.
The cross-links are due to ester or amide formation between functional groups.
Sulfone amide formation can be carried out following methods described in the literature, e . g.
The reduced boiling temperature also prevents or limits amide formation from the di-alkyl amine.
Where diacid is used, amide formation releases water in forming the amide functionality.
The compounds of formula Is can be prepared by amide formation according to Scheme 18.
Amide formation by acid-amine coupling.
One general procedure for amide formation is described below in Scheme 3.
LC / MS indicated completion of the first amide formation.
Amide formation can e.g.
By alkylation, acylation, ester formation or amide formation.
Scheme 25A depicts amide formation from either sulfonamide derivatives or amines.
Reduction of the azido function followed by amide formation gave 11.
Amide formation to afford ( X ) proceeds as described above.
By alkylation, acylation, ester formation or amide formation or the like.
Standard amide formation with substituted amines provided amide examples ( O ).
In some instances, an additional chemical transformation ( s ) was performed after amide formation.
In measure ( b ), the water formed by the amide formation will be distilled off.
The potential reactions include Michael conjugation, enamine formation, hydrazone formation, reductive amination, and amide formation.
Method 12, General procedure for amide formation using acylbenzotriazoles.
For amide formation reactions, EDC / HOBt or HBTU / DIEA / DMF was used as the coupling agent.
By alkylation, glycosylation, PEGylation, acylation, ester formation or amide formation or the like.
The amide formation is completed in about 6-8 hours.
Compound 10 can be converted to amide 11 by hydrolysis and subsequent amide formation coupling reaction.
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