Examples of 'amino acid at position' in a sentence
Meaning of "amino acid at position"
amino acid at position: a specific location within a sequence where a particular amino acid is located
How to use "amino acid at position" in a sentence
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amino acid at position
A hydrophobic or neutral amino acid at position i ;.
Preferably, the amino acid at position 8 of Formula XVIII is a valine or isoleucine.
In certain embodiments of the invention the amino acid at position 9 is altered.
Preferably, the amino acid at position 9 of Formula XIX is an asparagine or a phenylalanine.
The bound peptide consists of 8 amino acids plus a statine amino acid at position 5.
In some embodiments the amino acid at position 3 is glutamic acid.
The DNA sequences comprise a point mutation at the codon encoding the amino acid at position 12.
In one embodiment the amino acid at position 3 is glutamic acid.
In some embodiments, the glucagon analog comprises an aliphatic amino acid at position 16.
Preferably, the amino acid at position 1 of Formula XIX is a serine or asparagine.
In some embodiments, the analog comprises an acylated or alkylated amino acid at position 10.
Preferably, the amino acid at position 2 of Formula XIX is a histidine or an aspartic acid.
In exemplary aspects, the glucagon analog comprises an acylated or alkylated amino acid at position 10.
Preferably, the amino acid at position 3 of Formula XIX is a threonine or a glutamic acid.
In exemplary aspects, the glucagon analog comprises a large, aromatic amino acid at position 1.
See also
Ii the amino acid at position 2 is Ala or Gly.
The peptides and proteins of the present invention comprise an altered amino acid at position 119.
Preferably, the amino acid at position 5 is a glutamic acid.
Subsequently, the inventors focused on the amino acid at position 65 of ECFP.
The amino acid at position 5 replaced with an alanine ;.
In some embodiments, the amino acid at position 5 can be deleted.
Optionally, the peptide analogue comprises an N-alkylated amino acid at position 7.
In a further embodiment, the amino acid at position 28 is aspartic acid.
In some embodiments, the presently disclosed peptides comprise a DPP-IV protective amino acid at position 2.
In some aspects, the amino acid at position 18 is an aliphatic amino acid.
Optionally, the peptide analogue comprises an N-glycated amino acid at position 7.
For example, the amino acid at position 66 may be arginine or glycine.
A system according to claim 6 in which the negatively charged amino acid at position 66 is Glu.
In some aspects, the amino acid at position 17 is not a basic amino acid.
Similarly, a lysine can be added following the amino acid at position 105.
In some aspects, the amino acid at position 29 is a small aliphatic amino acid.
The method of claim 18 wherein a mutated codon encodes an amino acid at position 490.
In some embodiments, the amino acid at position 21 is an alpha helix promoting amino acid.
Br-AFP2 contains an unidentified uncommon amino acid at position 11.
The naturally occurring amino acid at position 149 could also be replaced with other amino acids.
The variant of claim 17 wherein the substituted amino acid at position 534 is histidine.
Preferably, the amino acid at position 10 of Formula XVIII is a valine or an methionine.
In exemplary preferred aspects, the amino acid at position 28 is Glu.
Preferably, the amino acid at position 16 of Formula XVIII is a leucine, serine or threonine.
In exemplary aspects, the DPP-IV protective amino acid at position 2 is Ala or Gly.
In some aspects, the amino acid at position 21 is Glu, homoglutamic acid or homocysteic acid.
In specific aspects, the a, a-disubstituted amino acid at position 16 is AIB.
In some aspects, the amino acid at position 27 is an amino acid other than Met.
In exemplary embodiments, the the a, a-disubstituted amino acid at position 20 is AIB.
In exemplary aspects, the amino acid at position 20 of the glucagon analog is Lys.
This transition is silent and does not change the encoded amino acid at position 119 ( F ).
This mutation changed the encoded amino acid at position 576 from asparagine to aspartic acid.
The amino acid at position 1 can, for example, be a large, aromatic amino acid.
In some specific embodiments, the amino acid at position 27 is leucine or norleucine.
The amino acid at position 20 replaced with glutamic acid ;.
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