Examples of 'amylin' in a sentence
Meaning of "amylin"
amylin (noun): A hormone that is produced by the pancreas and helps regulate blood sugar levels. Amylin works in conjunction with insulin to control glucose metabolism
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- The dextrin of starch.
- A pancreatic polypeptide hormone that is secreted with insulin by the beta cells of the islets of Langerhans, that is a major component of the amyloid deposits found outside beta cells in those affected with type 2 diabetes, and that inhibits the glucose synthesis stimulated by insulin in skeletal muscles.
How to use "amylin" in a sentence
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amylin
In vivo amylin agonist and antagonist responses.
Similar results have been obtained using amylin.
The genetic sequence of amylin is as listed as follows.
Amylin agonist compounds include various stereoisomers.
No direct effects of amylin on kidney tissue have been reported.
Amylin controls glucose homeostasis and gastric motility.
Agonists include amylin analogs and amylin derivatives.
Amylin for treatment of bone disorders.
Derivative of amylin according to the examples.
Another peptide of interest in the treatment of diabetes is amylin.
Additionally amylin is difficult to formulate as it precipitates at physiologic pH.
In a preferred embodiment an amylin agonist is pramlintide.
Human amylin binds to two distinct receptor complexes.
Similar results have been obtained with an infusion of amylin.
The stability of amylin preparations may be increased at neutral pH.
See also
Some weight maintenance was achieved with amylin monotherapy.
Preferably an amylin agonist analogue is used.
Amylin is associated with glycemic control and treatment of diabetes.
Insulin and amylin combination.
The amylin is added and stirred gently until it dissolved.
The structure and biology of amylin have previously been reviewed.
The term refers to compounds which mimic effects of amylin.
Examples of amylin agonists include pramlintide and the like.
Pentagastrin appears to enhance the ghrelin lowering effect of amylin.
The role of amylin also remains the subject of debate.
The product contains an analogue of human amylin called pramlintide.
Hyperamylinemia is defined as having an abnormally high blood amylin level.
Pramlintide is an amylin receptor agonist.
It is appreciated that deficiencies in insulin may parallel deficiencies in amylin.
Binding to human amylin receptors.
Amylin is a pancreatic hormone important in overall metabolism and in glucose homeostasis.
Methods of testing compounds for amylin activity are known in the art.
Amylin has been demonstrated to decrease food intake in mice and rats.
Evaluation of the binding of compounds to amylin receptors was carried out as follows.
A number of amylin agonists have been characterized using these biological assays.
We also have amylin.
It is believed that amylin acts through receptors present in plasma membranes.
A range of metabolic parameters following a single bolus dose of amylin was observed.
We have discovered that amylin is an anabolic hormonal partner for insulin.
Additional methods were similar to those described for amylin receptor assays.
Rat amylin was synthesized by standard solid phase peptide synthesis methods.
Such polypeptides may also be called pramlintide derivatives or amylin derivatives.
High affinity amylin binding sites are present in the rat nucleus accumbens.
Standard assay formats can be used to assay for amylin analogs.
Amylin is a hormone that is secreted by your pancreas at the same time as insulin.
Insulin responses are also significantly depressed by amylin infusions in fasted animals.
Agonist and analogs of amylin that contain less peptide character are provided.
The work on which this invention is based has been concerned with amylin.
The desired bioavailability of insulin and amylin agonist peptide or amylin is maintained.
Amylins and amylin analogs to which a chemical moiety is attached are amylin derivatives.
