Examples of 'ankyrin' in a sentence
Meaning of "ankyrin"
ankyrin: (noun) a protein that plays a key role in the integrity of the cytoskeleton in eukaryotic cells, especially in muscle cells
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- Any of a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton.
How to use "ankyrin" in a sentence
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ankyrin
They contain multiple ankyrin repeats.
Ankyrin repeats were originally recognised in the cytoskeletal protein ankryin.
Capping modules for designed ankyrin repeat proteins.
Ankyrin repeats are well known to the person skilled in the art.
Structural description of an ankyrin repeat unit.
An ankyrin repeat domain of a binding protein of the invention binds xSA.
These target interaction residues are hence forming a largecontact surface on the ankyrin repeat domain.
Examples of designed ankyrin repeat domains are shown in the Examples.
The filamentous network subjacent to the nodal membrane contains cytoskeletal proteins called spectrin and ankyrin.
The ankyrin repeats were revealed by a BLAST database search for protein homologies.
Oligonucleotides were designed to allow assembly PCR of the ankyrin repeat modules.
Ankyrin repeat and sterile alpha motif domain containing 3.
Vaccinia virus also contains Serpin genes and Ankyrin genes.
Preferably, said binding domain is an ankyrin repeat domain or designed ankyrin repeat domain.
All three IkBa-like proteins contain five ankyrin repeats.
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The 24 tandem ankyrin repeats are responsible for the recognition of a wide range of membrane proteins.
A bispecific binding agent of item 1 which is in the format of a bispecific ankyrin repeat molecule.
His-tag purification of a randomly chosen ankyrin repeat protein generated according to the present invention.
Ankyrin repeats typically fold together to form a single, linear solenoid structure called ankyrin repeat domains.
In a preferred aspect of the disclosure, the Ankyrin genes are completely truncated.
They were named for their interaction with the telomere-associated TRF1 proteins and ankyrin repeats.
Preferred is a binding protein comprising an ankyrin repeat domain that binds human serum albumin ( HSA ).
Ankyrin repeats are involved in protein-protein interactions in a variety of proteins P.
The C-terminus of class I proteins contains a number of ankyrin repeats and has transrepression activity.
NRCAM is described as single-pass type I transmembrane protein interacting with ankyrin.
A consensus sequence of the DAP-2 ankyrin repeats is shown at the bottom.
Hydrogen peroxide activates another receptor, known as transient receptor potential ankyrin 1, or TRPA1.
Ankyrin 1 links membrane receptor CD44 to the inositol triphosphate receptor and the cytoskeleton.
Transient receptor potential ankyrin 1 (TRPA1) is a member of the large family of TRP ion channels.
In a further example, a compound of the disclosure is a Designed Ankyrin Repeat Protein ( DARPin ).
Variation in a gene called Ankyrin 3 ( ANK3 ) showed the strongest association with bipolar disorder.
Preferably, said G at position 1 and / or S at position 2 of said ankyrin repeat domain are missing.
The ankyrin repeat module is a 33 amino acid polypeptide consisting of two antiparallel a-helices and a B-turn.
Background: the transient receptor potential ankyrin 1 channel (trpa1) mediates joint pain in arthritis.
Ankyrin contains 22 of these repeats.
We also identified in the on-going assembly of the wVulC genome, 66 ankyrin domain-encoding genes.
A single ankyrin repeat is a 33 residue motif consisting of two a-helices and a B-turn.
The transient receptor potential regarding the ankyrin type 1 ( TRPA1 ) channel.
Ankyrin repeat domain-containing protein 13C is a protein that in humans is encoded by the ANKRD13C gene.
The in pDST23 encoded POI is the designed ankyrin repeat protein ( DARPin ) 3a.
Particularly preferred motifs are selected from an SH2 domain, WD-40 repeats and ankyrin repeats.
SOCS proteins with ankyrin repeats are referred to as ASB 1-ASB3.
In a further example, a Fn14-binding protein of the disclosure is a Designed Ankyrin Repeat Protein ( DARPin ).
