Examples of 'anti-apoptotic' in a sentence
Meaning of "anti-apoptotic"
anti-apoptotic: describes a substance or agent that inhibits programmed cell death
How to use "anti-apoptotic" in a sentence
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anti-apoptotic
It has anti-apoptotic as well as proliferative effects.
Inhibitors are useful as anti-apoptotic agents.
Anti-apoptotic signaling pathways in mammalian cells.
Apoptosis inhibitors modulate the activation of anti-apoptotic molecules.
Genes encoding anti-apoptotic factors or agents could also be added.
This effect is referred to as the anti-apoptotic effect of NFkB.
Genes encoding anti-apoptotic factors or agents could also be applied.
The culturing conditions may be devoid of an anti-apoptotic agent.
For example, anti-apoptotic agents may be useful to minimize programmed cell death.
Metallothionein is a protein involved in anti-oxidative response and anti-apoptotic pathways.
Genes encoding anti-apoptotic or anti-necrotic factors or agents could also be added.
It is also a mucolytic and a hepatoprotectant, and it may have anti-apoptotic activity.
Xenon is neuroprotective vÃa an anti-apoptotic mechanism in both the cortex and the gyrus.
In contrast, activation of initiation caspases can still be blocked by anti-apoptotic events.
Preferably, an anti-apoptotic nucleic acid is used which comprises an exogenous nucleic acid.
See also
In some embodiments, an agent that induces cell immortality is an anti-apoptotic polypeptide.
Thus, the targeting of additional anti-apoptotic agents appears to provide therapeutic benefits.
Many different mechanisms exist to modulate the functions of pro - and anti-apoptotic proteins.
Overexpression of these anti-apoptotic proteins protects cancer cells against death signals of apoptosis.
These results suggest that stimulation of autophagia has anti-apoptotic and neuroprotective effects.
Various anti-apoptotic nucleic acids are known in the art, so that various embodiments are available.
In a specific embodiment, the expression of the anti-apoptotic transgene is specific to the pancreas.
UDCA is a naturally occurring bile acid with cytoprotective, membrane stabilizing and anti-apoptotic effects.
The balance between pro-apoptotic and anti-apoptotic proteins determines the fate of a cell.
However, the cell also contains countermine mechanisms to bypass this anti-apoptotic pathway.
Certain cells and viruses produce anti-apoptotic genes that function in the mitochondrial apoptotic pathway.
This stress response is most likely part of the cancer cell 's anti-apoptotic program.
Recent studies emphasize the importance of anti-apoptotic genes in cerebral protection which can rescue neurons.
Figure 17 shows that a combination of xenon and hypothermia interact synergistically to produce anti-apoptotic neuroprotection.
The mechanism underlying the anti-apoptotic effect of SAA is not clear at present.
DAXXp was found to have an important in vitro and in vivo anti-apoptotic activity.
We investigated the anti-apoptotic effect of MVs on PTEC cultured in different detrimental conditions.
Ultimately, none of these compounds provide efficient anti-apoptotic potential for motor neurons.
Anti-apoptotic mechanisms in cancerand their contribution to drug - andradio-resistance ;.
Activation of either receptor type can induce an anti-apoptotic state that prevents cell death.
Basically, the TA isoform induces cell death while the DN isoform is anti-apoptotic.
The peptides exhibit at least one activity selected from anti-apoptotic activity and anti-inflammatory activity.
Finally, anti-apoptotic proteins can be others such as fortilin, and the like.
Also, intracellular signaling cascades normally associated with anti-apoptotic actions are activated in theses areas.
An increased ratio of anti-apoptotic to pro-apoptotic proteins also decreases IR-induced apoptosis.
A rather surprising property of Daxx is its anti-apoptotic function.
The GC1 dendrimer has an anti-apoptotic effect on the human monocytes in culture in vitro.
In this context, AR is likely able to activate proliferative and anti-apoptotic signaling pathways.
Example 3 demonstrates the anti-apoptotic effect of AM extract using a murine model of eye damage.
These results clearly show that IFNY exerts an anti-apoptotic effect on SMCs.
Poxvirus anti-apoptotic strategies.
The Hippo pathway is a key inhibitor of the Yki proliferative and anti-apoptotic activity.
This is an anti-apoptotic protein.
The literature has not reached a consensus regarding the pro-or anti-apoptotic properties of FLIP.
In the myocardium, the anti-oxidative, anti-apoptotic and pro-metabolic properties of adiponectin has been observed.