Examples of 'antibody-drug' in a sentence
Meaning of "antibody-drug"
antibody-drug: A type of medication that uses antibodies to target specific cancer cells
How to use "antibody-drug" in a sentence
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Advanced
antibody-drug
The antibody-drug conjugate is typically lyophilized.
A method for producing an antibody-drug conjugate is not limited.
Antibody-drug conjugates and immunotoxins.
Two different types of antibody-drug complexes are then generated.
Antibody-drug conjugates and the use of same in therapy.
The unbound antibody or antibody-drug conjugate was removed by washing.
Antibody-drug conjugates were added in duplicates in the same day.
The kits include a container containing an antibody-drug conjugate.
This antibody-drug conjugate targets only cancerous cells.
Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods.
Antibody-drug conjugates are an emerging class of targeted immunotherapies for cancer.
Directly establishing the mass of the antibody-drug conjugate compound by mass spectrometry.
Antibody-drug conjugates have been developed as target-specific therapeutic agents.
Innate pharma and sanofi collaborate on next generation antibody-drug conjugates using.
An antibody-drug conjugate constitutes a means for selective delivery of a cytotoxic agent.
See also
antibody-dependent
antibody-dependent cellular cytotoxicity
antibody-drug conjugate
antibody-drug conjugates
This method may be employed to prepare the antibody-drug conjugates of the invention.
The antibody-drug conjugates can be administered to humans or to non-human animals.
In a particular embodiment, a moiety is hydrolyzed from the antibody-drug conjugate at the linker.
Two different types of antibody-drug or protein-drug complexes are then generated.
According to a specific preferred embodiment, the administration of the antibody-drug conjugate is performed by injection.
Antibody-drug conjugate produced by binding through linker having hydrophilic structure.
Despite the advances in preparing antibody-drug conjugates, current methods are limited by several factors.
The methods generally include administering to the subject an effective amount of an antibody-drug conjugate.
An antibody-drug conjugate wherein an antitumor compound represented by the following formula,.
The disclosure further provides an antibody-drug conjugate indicated above for use in therapy.
The antibody-drug conjugate compounds include pharmaceutically acceptable salts or solvates thereof.
The method of claim 1 wherein the antibody of the antibody-drug conjugate is a humanized antibody.
Compounds or the antibody-drug conjugates were added in duplicates in the same day.
The patient may be administered a chemotherapeutic agent in combination with the antibody-drug conjugate compound.
The in vitro potency of antibody-drug conjugates can be measured by a cell proliferation assay.
Is described as a production intermediate useful for producing the antibody-drug conjugate of the present invention.
The in vitro potency of antibody-drug conjugates can also be measured by a cytotoxicity assay.
Various delivery systems are known and they can be used for administering the antibody-drug conjugate.
Introducing the antibody-drug conjugate compound of step a into a mass spectrometer ; and subsequently.
The present invention also relates to a method for preparing the linkers and the antibody-drug conjugates.
They are jointly developing antibody-drug conjugates to track down and destroy tumor cells.
Antibody-drug conjugates use a monoclonal antibody that binds to tumors cells linked to a cytotoxic drug.
The present invention provides such antibody-drug conjugates for use in immunology and oncology.
The antibody-drug immune complexes can then detected using any suitable technique.
The pharmaceutical compositions include an antibody-drug conjugate and at least one pharmaceutically compatible ingredient.
The antibody-drug conjugate of the present invention can be administered with other cancer treating agent.
For administration, the anti-Axl monoclonal antibody or antibody-drug conjugate is formulated as a pharmaceutical composition.
The peptide antibody-drug bond facilitates rapid and efficient drug cleavage inside target tumor cell.
NRC scientists adapted this pipeline to produce antibody-drug conjugates used in immunotherapy.
The antibody-drug conjugate of any one of the preceding claims, wherein linker L further comprises a spacer.
The present invention is also directed to antibody-drug conjugates, and to compositions including the same.
Some Antibody-Drug conjugates include, or wherein S is thiol group of the Ligand unit.
The present invention relates generally to antibody-drug conjugates with anti-cancer activity and their medical uses.
The solution was concentrated by the Common procedure A to yield the titled antibody-drug conjugate.
Oncomatryx has developed antibody-drug conjugates that target proteins located in the tumor microenvironment.