Examples of 'antigen-presenting cells' in a sentence
Meaning of "antigen-presenting cells"
Antigen-presenting cells (APCs) are specialized immune cells that play a crucial role in the immune response by capturing, processing, and presenting antigens to other immune cells, such as T cells. They include macrophages, dendritic cells, and B lymphocytes. APCs are responsible for initiating and regulating immune responses against invaders, as well as maintaining immune tolerance and preventing autoimmune reactions
How to use "antigen-presenting cells" in a sentence
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antigen-presenting cells
Hydroxychloroquine increases lysosomal pH in antigen-presenting cells.
The antigen-presenting cells may be transduced in vitro.
Eosinophils function as antigen-presenting cells.
These antigen-presenting cells can be used as the active ingredient of a tumor therapeutic agent.
Dendritic cells in the mucosa are antigen-presenting cells.
Preferably the antigen-presenting cells are of human origin.
In this particular experiment, melanoma cells were used as antigen-presenting cells.
Facultative antigen-presenting cells can also be used.
Dendritic cell vaccines are able to activate antigen-presenting cells directly.
Langerhans cells are antigen-presenting cells involved in epidermal immunity.
These infected cells become the secondary antigen-presenting cells.
Paraformaldehyde-fixed antigen-presenting cells were prepared and analyzed as follows.
They have to be activated by the pMHC-I complexes of antigen-presenting cells APCs.
Preferably, antigen-presenting cells are DCs derived from human peripheral blood mononuclear leukocytes.
Another therapy that is contemplated is the administration of transduced antigen-presenting cells.
See also
T cells are switched on by antigen-presenting cells such as dendritic cells.
The expression of co-stimulatory molecules is a defining feature of professional antigen-presenting cells.
Selection of the appropriate adjuvant to activate antigen-presenting cells to stimulate immune responses, is required.
These cells are recognized by macrophages or dendritic cells, which act as antigen-presenting cells.
Use of allogeneic cell lines to load antigen-presenting cells to elicit or eliminate immune responses.
The present invention concerns inducing and / or activating antigen-presenting cells.
In certain preferred embodiments, the antigen-presenting cells are isolated from the bone marrow.
The immune tolerance is induced by presenting autoantigens onto antigen-presenting cells.
Alternatively, autologous antigen-presenting cells that have been pulsed with the peptides are administered.
In certain embodiments of the invention, macrophages and antigen-presenting cells were targeted.
For example, antigen-presenting cells can be cultured in a coluture solution containing such polypeptides.
Cancer vaccine comprising as an active ingredient antigen-presenting cells as disclosed herein.
As antigen-presenting cells pass through lymph nodes, they present antigen to lymphocytes residing there.
The cells according to this aspect are thus advantageously antigen-presenting cells.
The advantage of using the activated antigen-presenting cells of the present invention as a vaccine follows.
In yet other aspects, the adjuvant induces the activation of antigen-presenting cells.
Constitutive expression of a costimulatory ligand on antigen-presenting cells in the nervous system drives demyelinating disease.
In still yet further aspects, the cells expressing the polypeptide are antigen-presenting cells.
Furthermore, they must attach to antigen-presenting cells so that a normal immune response can occur.
An antigen-presenting cell vaccine is a vaccine made of antigens and antigen-presenting cells APCs.
Typical antigen-presenting cells are macrophages, dendritic cells and other phagocytizing and pinocytizing cells.
Cancer vaccine comprising as an active ingredient antigen-presenting cells of the present invention.
For example, the antigen-presenting cells may be cultured in a culture medium containing the above-described polypeptide.
The use dendritic cells or progenitors thereof as antigen-presenting cells is disclosed herein.
In a second step, the antigen-presenting cells loaded with the peptide are reinjected into the patient.
Langerhans cells and skin dendritic cells are major antigen-presenting cells in the skin.
The obtained antigen-presenting cells are re-administered to the subjects to induce CTL in the subjects.
Cells transduced with these vectors will become more effective antigen-presenting cells.
Preferably, exosomes are prepared using antigen-presenting cells obtained from a subject of treatment and / or prevention.
Also disclosed is a composition and method that induces and / or activates antigen-presenting cells.
Embryonic stem cells and / or antigen-presenting cells may be isolated from the transgenic mouse.
The lysis of such necrotic cells is a rich source of antigens for antigen-presenting cells.
Macrophages may be isolated to serve as antigen-presenting cells autologous to the host T-cells.
The mucosal membrane contains numerous dendritic cells which arc excellent antigen-presenting cells.
The CTL and antigen-presenting cells may be autologous or heterologous to the patient undergoing therapy.
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Examples of using Antigen-presenting
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An example of an antigen-presenting cell is a dendritic cell
Hydroxychloroquine increases lysosomal pH in antigen-presenting cells
The antigen-presenting cells may be transduced in vitro
