Examples of 'antimetabolite' in a sentence
Meaning of "antimetabolite"
antimetabolite (adjective) - Relating to a class of drugs that interfere with the growth of cancer cells by substituting for essential nutrients needed for cell division
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- Any substance that competes with, or inhibits the normal metabolic process, often by acting as an analogue of an essential metabolite
How to use "antimetabolite" in a sentence
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antimetabolite
The preferred antimetabolite chemotherapeutic agent is gemcitabine.
Cladribine is a purine nucleoside analogue acting as an antimetabolite.
It is a member of the antimetabolite class of cytotoxic agents.
A large class of antiproliferative agents includes antimetabolite compounds.
Ethionine is an antimetabolite and methionine antagonist.
The large class of antiproliferative agents includes antimetabolite compounds.
Methotrexate is an antimetabolite of the antifolate type.
They have been described in patients undergoing treatment with alkylating or antimetabolite agents.
It is an antineoplastic antimetabolite with immunosuppressant properties.
Gemcitabine is a vicinol difluorine substituted deoxycytidine analogue which functions as an antimetabolite chemotherapeutic drug.
The antimetabolite may be a pyrimidine antagonist.
Mercaptopurine is in the thiopurine and antimetabolite family of medications.
The antimetabolite used in accordance with the invention is gemcitabine.
It is assumed to be an antimetabolite of arginine.
The antimetabolite anticancer agent may be an antifolate anticancer agent.
See also
Mercaptopurine is an antimetabolite of purines.
Both antimetabolite and steroid therapies are general immunosuppressive treatments with ocular and systemic side effects.
It is an antimetabolite.
The antimetabolite sulfanilamide inhibits sporulation in Saccharomyces cerevisiae strain API.
Antitumor antibiotics are a class of antimetabolite drugs that are cell cycle nonspecific.
It is classified as a purine analog, which is a type of antimetabolite.
That a lower dose of antimetabolite is used oftentimes lessens the side effects observed in a subject.
In other embodiments, the cytotoxic agent is an antimetabolite.
Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures.
In certain embodiments, the cytotoxic agent is an antimetabolite.
MTX is an antimetabolite drug used in treatment of cancer and autoimmune diseases.
In one embodiment, the chemotherapeutic agent is an antimetabolite.
The maximum effect of the antimetabolite Alimta is given for comparison.
In a preferred embodiment, the proliferation assay is an antimetabolite assay.
Many DNA lesions created by antimetabolite chemotherapy are repaired by BER.
In certain embodiments, the cytotoxic or immunosuppressive agent is an antimetabolite.
Clofarabine is a purine nucleoside antimetabolite marketed in the US and Canada as Clolar.
In some embodiments, the cytotoxic or immunosuppressive agent is an antimetabolite.
DHFR can also be used for antimetabolite resistance to methotrexate Wigler et al.
A composition of claim 13 wherein the second anticancer drug is an antimetabolite.
In one embodiment, the antimetabolite is a nucleoside analogue.
It consists of monoclonal antibody rituximab and high-dose antimetabolite cytarabine.
As disclosed herein, the antimetabolite agent is a cytidine analog.
The use of claim 1, wherein said antiproliferative agent is an antimetabolite drug.
As disclosed herein, the antimetabolite agent is a pyrimidine analog.
The method according to item 1, wherein said chemotherapeutic agent is an antimetabolite agent.
Methotrexate - is an antimetabolite and antifolate drug.
The antimetabolite anti-cancer agent according to the claims is gemcitabine or a salt thereof.
Methotrexate earlier known as amethopterin, is an antimetabolite and antifolate drug.
Also, antimetabolite resistance can be used as the basis of selection.
A product according to claim 1 or 2 wherein the antimetabolite compound is a cytidine analog.
Methotrexate is an antimetabolite which acts principally by competitively inhibiting the enzyme, dihydrofolate reductase.
In some cases, the anticancer therapy comprises therapy with a purine analog antimetabolite.
In another embodiment, the antimetabolite is the nucleoside analog fluorouracil.
The use as claimed in claim 1 wherein said chemotherapy agent is an antimetabolite chemotherapy agent.
