Examples of 'apoe' in a sentence
Meaning of "apoe"
APOE (noun): Stands for Apolipoprotein E, a protein involved in the metabolism of fats in the body. In scientific or medical contexts, APOE plays a role in cholesterol transport and is linked to certain health conditions. Example: Researchers studied the effects of APOE variants on cardiovascular health
How to use "apoe" in a sentence
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apoe
Metabolic regulation of apoE production in humans.
One ApoE gene is inherited from each parent.
But there are different variants of the ApoE gene.
Assays to measure ApoE activity are known in the art.
Immunotherapy regimes dependent on ApoE status.
The three introns of the ApoE gene are denoted as lines.
Geographically distinct populations have differing frequencies of apoE alleles.
A normal cellular function of ApoE is uptake and delivery of lipids.
There are three common alleles that encode apoE in humans.
Antibodies specific for ApoE are readily made and are known.
These functional differences confer pathophysiological properties to select ApoE isoforms.
Peptides and derivatives from ApoE and ApoB were a particular focus.
The ApoE amounts in the cells were determined by the method described above.
Serum levels of apoB and apoE are not different between genotypes.
An ApoE knockout rat provides a means to study various types of disorders and diseases.
See also
All patients were genotyped at the apoE locus as discussed further below.
The changes in apoE were probably brought about by a change in diet in ancestral humans.
In these studies a direct correlation between ApoE and inhibition was established.
The relative ApoE expression was determined using the AACt method.
Some studies have assessed the possible relationship between apoE polymorphism and atherosclerosis.
A role for the ApoE gene was initially suspected but could not be confirmed.
Examples of primers effective for amplification and identification of the ApoE isoforms are described therein.
The synthesis of apoE is carried out by the liver and weakly by the intestine.
Pooled plasma from healthy human subjects with known apoE level was used as a standard.
The interaction between ApoE with these receptors gives a basis for the metabolic regulation of cholesterol.
Landreth and his colleagues chose to explore the effectiveness of bexarotene for increasing ApoE expression.
ApoE is instrumental in lipoprotein metabolism in several ways.
This data reveals that PPARδ mediates the fatty acid repression of the apoE gene expression.
ApoE helps transport cholesterol in the blood.
This suggests that lack of apoE increases predisposition to fractures and OP.
ApoE genotype was not related to coronary function.
LXR increases the expression of apoE and increases the lipidation of apoE.
ApoE genotyping was carried out using standard techniques.
The work presented highlights two new roles of apoE in HCV pathogenesis.
ApoE is primarily synthesized in the liver.
This is also consistent with the well know association of ApoE and AD.
ApoE was previously thought to be involved only in cholesterol transport and metabolism.
This microscopic image shows the merging of APP and apoE in brain cells.
ApoE production following the procedures described above for rAAV.
The article demonstrates that passive immunization against apoE can attenuate AB accumulation.
ApoE genotyping may help guide lipid treatment when cardiovascular risks are high.
The lower panel shows the LTVEC for modifying the rat ApoE locus.
ApoE knockout mice exhibit severe hypercholesterolaemia and develop spontaneous atherosclerotic lesions.
These include CRP and ApoE.
ApoE is polymorphic and its various isoforms exhibit distinct functional and structural properties.
The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants IDL.
ApoE knockout animals display impaired clearing of lipoproteins from the blood and develop atherosclerosis.
Different Strategies for Treating or Monitoring depending on ApoE.
Different ApoE isoforms can modulate AB levels.
A few, rare individuals lack a functional ApoE gene.
