Examples of 'asfotase' in a sentence
Meaning of "asfotase"
asfotase (noun) - A type of enzyme replacement therapy used to treat a rare genetic disorder called hypophosphatasia, in which the body produces low levels of an enzyme called alkaline phosphatase
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- A drug used to treat hypophosphatasia.
How to use "asfotase" in a sentence
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asfotase
There is no experience with overdose of asfotase alfa.
Asfotase alfa interferes with alkaline phosphatase measurements.
It contains the active substance asfotase alfa.
The model identified body weight to affect asfotase alfa clearance and volume of distribution parameters.
No interaction studies have been performed with asfotase alfa.
Substance asfotase alfa.
Strensiq contains the active substance asfotase alfa.
Pharmacokinetic data from all asfotase alfa clinical trials were analysed using population pharmacokinetic methods.
The active substance is asfotase alfa.
The effects of asfotase alfa on x-ray appearance.
There is insufficient information on the excretion of asfotase alfa in human milk.
Asfotase alfa contains a catalytic domain of tissue non-specific alkaline phosphatase.
There are no data from the use of asfotase alfa in pregnant women.
If asfotase alfa is present in clinical laboratory samples, aberrant values could be reported.
There are insufficient data from the use of asfotase alfa in pregnant women.
See also
Asfotase alfa is a recombinant glycoprotein that contains the catalytic domain ( the active site ) of TNSALP.
Two patients experienced injection site reactions that led to reductions of their asfotase alfa dose.
The dose of asfotase alfa was increased for 11 patients during the study.
Breast-feeding should be discontinued during treatment with asfotase alfa.
Based on its structure and pharmacokinetics, asfotase alfa is unlikely to affect Cytochrome P-450 related metabolism.
Each ml of solution contains 100 mg of asfotase alfa.
All patients began the study on a dose of asfotase alfa 6 mg / kg per week.
