Examples of 'aspartyl' in a sentence
Meaning of "aspartyl"
Aspartyl is a term used in biochemistry to refer to a type of amino acid or a compound containing an aspartic acid group
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- The univalent radical obtained by removal of a hydrogen atom from the carboxylic acid group of aspartic acid
How to use "aspartyl" in a sentence
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aspartyl
Nearly all known aspartyl proteases are inhibited by pepstatin.
Chymosin is a member of the family of proteases known as aspartyl endopeptidases.
The aspartyl phosphate residue is then active in signaling.
This feature is not found in any other aspartyl protease.
Aspartyl phenylalanine methyl ester.
Plasmepsins are essential aspartyl protease enzymes of the malarial parasite.
Aspartyl phosphate to aspartate semialdehyde.
Angle of the aspartyl.
Cathepsin d is an aspartyl endopeptidase involved in many pathological processes when overexpressed.
Two different approaches were used to prepare the new aspartyl protease inhibitors.
Sulfonamides which act as aspartyl protease inhibitors are those of the following formula.
Removal of all four carborane moieties substantially reduces inhibition of aspartyl proteases.
The aspartyl aminopeptidase inhibitor is a selective DNPEP inhibitor.
The caspase family consists of at least fourteen related cysteine aspartyl proteases.
HIV aspartyl protease.
See also
The present invention relates to prodrugs of a class of sulfonamides which are aspartyl protease inhibitors.
Heterocyclic aspartyl protease inhibitors, preparation and use thereof.
These enzymes are typically recognised as possessing two aspartyl residues at the active site.
In one embodiment, the aspartyl aminopeptidase inhibitor is a small molecule.
The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors.
In an embodiment, the aspartyl aminopeptidase inhibitor is not a methionine aminopeptidase inhibitor.
Asparaginyl and glutaminyl residues can be deaminated to the corresponding aspartyl or glutamyl residues.
The ineffectiveness of inhibition of aspartyl peptidase ( s ) by pepstatin is consistent with prior literature.
These references do not disclose the use of the compounds as aspartyl protease inhibitors.
Renin is a highly specific aspartyl protease of the renin-angiotensin system initially synthesized as preprorenin.
Glutaminyl and asparaginyl residues are frequently deamidated to the corresponding glutamyl and aspartyl residues.
Aromatic derivatives as HIV aspartyl protease inhibitors.
Glutaminyl and asparaginyl residues may be deamidated to the corresponding glutamyl and aspartyl residues.
HIV and HTVL viruses rely upon their aspartyl proteases for viral maturation.
Such compounds inhibit the proteolytic processing of viral polyprotein precursors by inhibiting aspartyl protease.
Truncated secretory aspartyl proteinase 2.
The compound inhibits the proteolytic processing of viral polyprotein precursors by inhibiting aspartyl protease.
Removal of the t-butyl group from the aspartyl residue yields eptifibatide.
Glutaminyl and asparaginyl residues are frequently deamidated to the corresponding gluramyl and aspartyl residues.
The at least one aspartyl aminopeptidase inhibitor and the at least one chymase inhibitor, or.
These compounds illustrate the drawbacks concomitant to pharmaceutical compositions comprising hydrophobic aspartyl protease inhibitors.
A pharmaceutical composition comprising an aspartyl aminopeptidase inhibitor and a pharmaceutical composition comprising a chymase inhibitor, or.
These compounds are especially well suited for inhibiting HIV aspartyl protease.
In one embodiment, the aspartyl aminopeptidase is not APA.
Therefore, we sought to identify novel human aspartyl proteases.
In one embodiment, the aspartyl aminopeptidase is not APN.
In certain embodiments, asparaginyl residues may be deamidated to aspartyl residues.
In another embodiment, the aspartyl aminopeptidase inhibitor is not Amastatin.
In certain instances, asparaginyl residues may be deamidated to aspartyl residues.
Thus, Amastatin is an aspartyl aminopeptidase according to the definition herein.
G = optionally present and is a hydrophilic moiety, preferably an aspartyl amide moiety.
In one embodiment, the aspartyl aminopeptidase inhibitor is Amastatin or a derivative thereof.
However, the codon corresponding to the isomerizable aspartyl residue must be changed.
In an embodiment, the aspartyl aminopeptidase inhibitor is not a selective aminopeptidase A inhibitor.
It shows protease activity which can be inhibited by pepstatin, a specific inhibitor of aspartyl proteases.
