Examples of 'autoantigen' in a sentence
Meaning of "autoantigen"
Autoantigen is a type of antigen that originates within an individual's own body. It triggers an immune response leading to autoimmune diseases
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- Any antigen that stimulates autoantibodies in the organism that produced it; an antigen produced by the self (that is, by one's own tissues).
How to use "autoantigen" in a sentence
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autoantigen
The autoantigen may be an endogenous human protein.
The peptide may be an antigen or may be an autoantigen.
The autoantigen presenting cells are then tolerated.
The present invention relates to adrenal autoantigen.
T cell responses to insulin as an autoantigen have also been described.
The antigen may be a tumor antigen or an autoantigen.
Any autoantigen can be employed.
It is not at present known whether insulin is also an autoantigen.
The autoantigen can be located on a fibroblast or any other cell type.
The antigen to be conjugated will therefore normally be an autoantigen.
The autoantigen may be any associated with any autoimmune disease.
The peptide used in such treatment is an autoantigen peptide.
The autoantigen can be linked to the antibody by any suitable method.
Described herein is an example where the vaccine autoantigen is proteolipid.
The autoantigen may be a pathogenic antigen in the pathophysiology of the autoimmune disease.
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The method may be used to desensitise an individual to a polypeptide autoantigen.
More preferably the target autoantigen has been prepared from a cow.
The hypothetical causal agents include environmental and autoantigen aspects.
Such fragments need not possess the autoantigenic properties of the entire autoantigen.
The antigen binding site of the IgE antibody binds to an autoantigen.
We have isolated a cDNA molecule encoding an autoantigen associated with endometriosis.
This was carried out by feeding a subject with low doses of the autoantigen.
Meaning of autoantigen.
No autoantigen has been definitively associated with the development of inflammation in JDM.
Of particular interest are the human and mouse autoantigen segments.
The raw result recorded for each autoantigen tested with individual samples was the median value.
The vaccine may be formulated with one or a cocktail of autoantigen sequences.
The antibody / autoantigen construct includes an autoantigen linked to an antibody.
Possible therapeutic strategies based on this autoantigen have also been reported.
The vector comprises a DNA sequence encoding at least a portion of a myelin protein autoantigen.
Specific primers were synthesized to amplify the putative autoantigen gene from the chondrocyte cDNA.
In other words, an autoantigen is an antigen that is subject to autoimmune destruction.
The present data further confirm that tTG is a major autoantigen in coeliac disease.
In addition, the autoantigen may be any autoantigen disclosed herein above.
The integral membrane protein PIP is a dominant autoantigen of myelin.
To direct delivery of the autoantigen vía the antibody, the two are linked.
In one embodiment the said SMFLTAA is a fluorescently labelled target autoantigen isolated from a mammal.
The autoantigen ( or related peptide ) is added to the lymphocyte cultures for several days.
Human PSA is essentially an autoantigen in the rhesus monkey.
The T cells target and react with the linked autoantigen.
We isolated and identified BiP as an autoantigen in RA by using proteomics.
Free DNA or DNA debris from necrotic and apoptotic cells can act as an autoantigen.
The column fraction containing the adrenal autoantigen may be determined by Western blotting.
The use of claim 3 wherein the antigen is an autoantigen.
It has been identified as autoantigen in type 1 diabetes.
In this way, endogenous myostatin may be rendered an effective autoantigen.
The method of claim 1 wherein said autoantigen is myelin basic protein.
The method of claim 20 wherein the mammalian transplantation antigen is an autoantigen.
However, it does not show immunoreaction against autoantigen and self tolerance is established.
In other embodiments, the second polypeptide antigen is obtained or derived from an autoantigen.
