Examples of 'autophosphorylation' in a sentence
Meaning of "autophosphorylation"
Autophosphorylation: a process in which a protein kinase phosphorylates itself
Show more definitions
- The phosphorylation of a kinase protein catalyzed by its own enzymatic activity
How to use "autophosphorylation" in a sentence
Basic
Advanced
autophosphorylation
This is an autophosphorylation site in the activation loop.
The results are expressed as a percentage of inhibition of the autophosphorylation.
Autophosphorylation can be achieved by a number of means.
Activation leads to a process called autophosphorylation.
The role of αCaMKII autophosphorylation in the establishment of alcohol addiction.
Activity was assessed by autophosphorylation.
Kinase autophosphorylation controls were carried out in the same conditions.
No substrate is needed because of autophosphorylation on enzyme.
Some autophosphorylation could be detected.
This kinase undergoes autophosphorylation.
The former is an autophosphorylation site and is linked to activation of the protein.
The binding of insulin to its receptor results in autophosphorylation of the domain.
This is an autophosphorylation reaction.
A direct way to assess specific activation of rPTKs is by analysis of receptor autophosphorylation.
The inhibition of autophosphorylation is the objective pursued with kinase inhibitors.
See also
The phosphorylation of growth factor receptors in response to ligand binding is known as autophosphorylation.
Autophosphorylation allows enzymes to be fully activated prior to addition to peptide substrates.
It binds to the intracellular phosphorylation domain to prevent receptor autophosphorylation upon ligand binding.
This autophosphorylation is required for subsequent activity of the insulin receptor.
Binding of the ligand triggers receptor dimerization and autophosphorylation of the internal receptor domain.
Autophosphorylation enzyme assay.
The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation.
The autophosphorylation is essential for the interaction of the receptor with its substrates.
The insulin receptor has three similar autophosphorylation sites on the activation loop and juxtamembrane region.
The autophosphorylation stabilizes the activated receptor kinase resulting in a phosphorylation cascade involving intracellular signaling proteins.
Receptor binding of IGFI results in autophosphorylation of tyrosine residues.
It shows that the autophosphorylation observed is dependent upon the time of the phosphorylation reaction.
One consequence of this kinase activation is the autophosphorylation of EGFR on tyrosine residues.
Autophosphorylation enhances IR kinase activity and triggers downstream signaling events.
The Figure also includes autophosphorylation controls of each of these kinases.
The clone was expressed in COS cells and found to be functional in autophosphorylation studies.
Numerous autophosphorylation sites have been identified that serve as markers for activated PAK.
Binding of EGF to the receptor causes activation of the kinase and subsequently receptor autophosphorylation.
The EGFR autophosphorylation inhibition was evaluated using the same procedure as described hereinbefore.
One test for activating ligands is the HRG tyrosine autophosphorylation assay described below.
DMBI inhibits the autophosphorylation and dimerization of FGFR and PDGF type receptors.
Fractions were tested in HRG tyrosine autophosphorylation assay.
The autophosphorylation level was determined Sandwich-ELISA technique.
A compound of formula I inhibits the autophosphorylation of the SCF receptor in the micromolar range.
Phosphorylation of SPS is mediated by ERK autophosphorylation.
The induction of Ret autophosphorylation by GDNF was dosage dependent.
Reduced levels of membrane-derived oligosaccharides result in autophosphorylation of RcsC.
For example, autophosphorylation may be measured, in accordance with established assay procedures.
KaiA augments kaiC autophosphorylation.
Kinase-active IRAKs may be capable of transphosphorylation of other proteins or autophosphorylation.
This activation leads to autophosphorylation of tyrosines and induction of the RET-dependent signal.
In addition, the sample enhanced the ability of insulin to stimulate autophosphorylation.
A method for measuring the autophosphorylation of a tyrosine kinase receptor comprising the steps of,.
The subject compositions can also be used to stimulate autophosphorylation of pp60 src.
Autophosphorylation of DCAMKL2 strongly reduces its affinity for MTs.
