Examples of 'avibactam' in a sentence
Meaning of "avibactam"
avibactam (noun): A specific type of antibiotic medication used in combination with other drugs to treat bacterial infections
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- A particular non-β-lactam β-lactamase inhibitor antibiotic
How to use "avibactam" in a sentence
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avibactam
It is unknown whether avibactam is excreted in human milk.
The active substances are ceftazidime and avibactam.
No metabolism of avibactam was observed in human liver preparations microsomes and hepatocytes.
Carcinogenicity studies have not been conducted with avibactam.
Avibactam to meropenem.
Zavicefta contains the active substances ceftazidime and avibactam.
Elimination of ceftazidime and avibactam is decreased in patients with moderate or severe renal impairment.
Zavicefta is an antibiotic medicine that contains two active substances ceftazidime and avibactam.
Providing a solution comprising avibactam sodium and water ;.
The active substances in Zavicefta are ceftazidime and avibactam.
Avibactam blocks the action of bacterial enzymes called beta-lactamases.
A subject matter of the present invention is a crystalline form C of avibactam sodium.
Unchanged avibactam was the major drug-related component in human plasma and urine following dosing with.
In a first step, an aqueous solution of avibactam sodium is prepared.
Crystalline form C of avibactam sodium obtainable or obtained by the process according to claim 8.
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Hence, for pharmaceutical purposes anhydrous forms of avibactam sodium are preferred over hydrates.
Animal studies with avibactam do not indicate harmful effects with respect to fertility see section 5.3.
Also, some bacteria are resistant to cephalosporins by other mechanisms, and therefore avibactam does not work.
Animal studies with avibactam have shown reproductive toxicity without evidence of teratogenic effects see section 5.3.
Preferably, the pharmaceutical composition is free or essentially free of form A of avibactam sodium.
Synergy was observed for avibactam with ceftazidime in the Burkholderia cepacia complex . [ 5 ].
Each vial contains ceftazidime pentahydrate equivalent to 2 g ceftazidime and avibactam sodium equivalent to 0.5 g avibactam.
Avibactam showed no significant inhibition of cytochrome P450 enzymes in vitro.
The human protein binding of both ceftazidime and avibactam is approximately 10 % and 8 %, respectively.
Avibactam and ceftazidime showed no in vitro cytochrome P450 induction at clinically relevant concentrations.
The terminal half-life ( t ½ ) of both ceftazidime and avibactam is about 2 h after intravenous administration.
Avibactam inhibits some ( but not all ) bacterial ß-lactamases.
