Examples of 'binding pocket' in a sentence
Meaning of "binding pocket"
binding pocket: A pocket, usually on a garment or bag, that securely holds or contains items such as documents, cards, or small objects due to being designed with specific closures or features to prevent items from falling out
How to use "binding pocket" in a sentence
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binding pocket
The catalytic zinc was located in the binding pocket.
This binding pocket is in the catalytic active site of the kinase domain.
Such associations may occur with all or part of the binding pocket.
The ligand binding pocket is small and contains aromatic and basic residues.
The analogues were evaluated to probe a putative hydrophobic binding pocket of opioid receptors.
Their hydrophobic binding pocket gives them the ability to reversibly bind odorant molecules.
Such associations may occur with all or any parts of the binding pocket.
The binding pocket for the pair of reactants was too open and activity was low.
The differences in methylation patterns of PRMTs arise from restrictions in the arginine binding pocket.
Amino acids that form the extended substrate binding pocket of exemplary proteases are described herein.
The grey spheres represent the calcium atoms bound in the ligand binding pocket.
A VFR is part of the antigen binding pocket or groove that may contact antigen.
The researchers then created mutations that destroyed the binding pocket for ppGpp.
As a result of its shape the binding pocket accommodates the RNA cap or analog thereof.
The cleft consists of the GAR binding site and the folate binding pocket.
See also
A binding pocket can often be a particular shape, indentation, or cavity in the binding site.
This is because more Van der Waals interactions can occur between sugar and binding pocket.
Within the ATP binding pocket.
According to one embodiment, said mutation is a substitution in the putative folate binding pocket.
In particular, residues comprising parts of the substrate binding pocket are targeted by cassette mutagenesis.
The promiscuous binding pocket of P-gp is lined with aromatic amino acid side chains.
The P group preferably fits in the aryl binding pocket of thrombin.
A common binding pocket for ATP and the inhibitor geldanamycin is situated in the N-terminal domain.
For example, by enlarging or decreasing the asparagine binding pocket.
The discovery of this peculiar binding pocket is the subject-matter of the present invention.
Firstly, there is high shape complementarity between the binding pocket and biotin.
Tight binding or a good fit in the binding pocket model correlates with potent BTK-inhibitory activity.
When in this conformation, imatinib fits nicely into the binding pocket of KIT.
For example, the glycan binding pocket of avian HA is narrow.
Notably, both residues do not overlap with residues of the orthosteric FGF binding pocket.
The 4-ethyl acetamide is included to occupy the binding pocket about the coumarin ring system.
PFP binding pocket size - binding of the PFP ester and direction.
All compounds identified were docked into the binding pocket of Stat3 SH2 domain in silico.
The binding pocket contains metal ion ( zinc and magnesium ) binding sites.
Figure 4 demonstrates clustering of mutations at critical sites within the ATP - binding pocket of EGFR.
Identifying a binding pocket in the model of protein X ;.
Figure 16 provides a closer view of the catalytic binding pocket.
Asn54 may be involved in the binding pocket for the substrate.
However, the hydoxyl group of tyrosine 735 was orientated away from the ligand binding pocket.
Figure 16B depicts the binding pocket showing equisite shape complementarity.
Table 2 - Residues corresponding to the binding pocket.
The final side of the ATP binding pocket is conveniently named the “ ATP lid . ”.
Protein stability - especially, the stability of a PFP binding pocket.
The VH and VL chains form a binding pocket that has been referred to as F ( v ).
The second one was the evaluation of the mimics filling the Phe-43 binding pocket.
HLA binding pocket or at least partly on the HLA binding face of KIR3DL2 protein.
Therefore, they probably share the same binding pocket with LPS . ".
The ligand binding pocket is bordered by predominant hydrophobic residues ( FIGS . 4 b and 4 c ).
Two cysteine mutations were also constructed in the binding pocket itself ( Figure 1 ).
The binding pocket of the enzyme prefers long chain, E, E, dienes such as,.
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Examples of using Pocket
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Fold both pocket pieces to wrong side
You sold schools to line your pocket
In the breast pocket of my overcoat it was hanging here
