Examples of 'biologically active moiety' in a sentence
Meaning of "biologically active moiety"
Biologically active moiety: Refers to the specific part of a molecule or compound that is responsible for its biological activity or function. In drug development, this term is used to describe the pharmacologically active component of a drug that produces a specific effect in the body
How to use "biologically active moiety" in a sentence
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biologically active moiety
The biologically active moiety can be a drug.
Prodrugs are typically formed by chemical modification of a biologically active moiety.
Levonorgestrel is the biologically active moiety of racemic norgestrel.
A further advantage of the present invention is the release of an unmodified biologically active moiety.
A biologically active moiety may comprise a complete protein or biologically active portion thereof.
The linker used is attached to the biologically active moiety vía ester group.
Biologically Active Moieties The polypeptides of the invention comprise at least one biologically active moiety.
In this construct the biologically active moiety comprises FVII as a single chain.
The polypeptide of claim 1 comprising a second biologically active moiety.
Indolizine, a biologically active moiety.
In one embodiment, the polypeptide comprises one biologically active moiety.
In one embodiment, a biologically active moiety comprises the mature form of a protein.
In a preferred embodiment of the present invention, the biologically active moiety is a drug.
In one embodiment, a biologically active moiety is derived from a fibronectin binding molecule.
Therefore, enzyme-independent autocatalytic cleavage of carrier and biologically active moiety is preferred.
See also
biologically active fragment
biologically active material
biologically active molecule
biologically active molecules
biologically active material
biologically active molecule
biologically active molecules
The second biologically active moiety comprises a heavy chain of a clotting factor ;.
In the present invention, the biologically active moiety is a drug.
The first biologically active moiety comprises a light chain of a clotting factor ; and.
The composition of claim 1, wherein the biologically active moiety is a somatropin.
The biologically active moiety is released from the prodrug upon cyclization-activation by cyclic imide formation.
In one embodiment, at least one biologically active moiety comprises a clotting factor.
In some embodiments, the compounds provided herein can be conjugated to a biologically active moiety.
The compound of claim 2 wherein said biologically active moiety is a phosphoramide mustard or a phosphorodiamidate mustard.
In another aspect, the conjucate of Formula II comprise one biologically active moiety.
In certain embodiments, a biologically active moiety of the invention comprises a single domain binding molecule e . g.
The composition of claim 1 to 6, wherein the biologically active moiety is insulin.
In other embodiments, a biologically active moiety of the invention comprises a binding site from a repeat protein.
The chimeric nodavirus-like particle of claim 23 wherein the biologically active moiety is an immunostimulant.
In another embodiment, a biologically active moiety of the invention comprises a binding site from a cysteine-rich polypeptide.
Figure 10 shows an scFc molecule comprising IFN-B as the biologically active moiety.
The Biologically Active Agent The biologically active moiety or drug is a substituted or unsubstituted 5-nitrothiazole.
In one aspect, the oligomeric conjugate of Formula II comprises a biologically active moiety T1-T2.
Spacer region 2 contains a biologically active moiety 3, in this case a ribozyme ; flanked by ribonucleotide strings 4.
Within the compounds of formula ( III ), R6 designates a biologically active moiety.
In a preferred embodiment the biologically active moiety is included within substituent R ₂ ( Formula I ).
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