Examples of 'bombesin' in a sentence
Meaning of "bombesin"
Bombesin is a peptide hormone that is involved in various physiological processes in the body. It is commonly found in the gastrointestinal tract and the central nervous system
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- A neural oligopeptide that stimulates the release of gastrin
How to use "bombesin" in a sentence
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bombesin
Immunohistochemistry with bombesin antibody staining was performed.
Bombesin analog peptide antagonist conjugates.
Several kinds of bombesin antagonists are now known.
Bombesin is a peptide originally isolated from frog skin.
The invention provides peptides which are analogs of bombesin.
Several kinds of bombesin antagonists have now been characterized.
The compounds have proved to be antagonists of bombesin receptors.
Effects of bombesin was used as positive control.
This invention is for compounds which are bombesin receptor antagonists.
Bombesin and related peptides.
Prior to the bombesin injection.
The compounds of the instant invention are highly selective antagonists of bombesin receptors.
The two bombesin antagonists are synthesized by solid phase methods.
A clear punctate perinuclear staining is detectable for bombesin treated cells.
Irreversible bombesin antagonists.
See also
Intravenous injection of bombesin ca.
They are all bombesin analogs containing seven to ten amino acid residues.
A number of these cancers are known to secrete peptide hormones related to GRP or bombesin.
These results were surprising for bombesin stimulates growth of normal pancreas tissue.
Other bombesin analogs were prepared by making appropriate modifications of the following synthetic method.
The most particularly preferred pseudopeptide bombesin antagonists in the present invention appear below.
Several patents and patent applications refer to metal labeled Bombesin agonists.
The complexation of the bombesin analogs with natIn was performed following the same protocol.
Fibroblasts from two schizophrenic patients also had normal TEA and bombesin responses.
Since then several types of Bombesin antagonists have been reported.
The bombesin antagonists of Formula I may be synthesized by solid phase synthesis.
Since then several types of Bombesin antagonist have been reported.
At least two synthetic protocols may be followed to produce the Formula I pseudopeptide bombesin antagonists.
This invention relates to novel Bombesin analogs which are potentially useful as pharmaceuticals.
Bombesin was stored as a 1mM solution in distilled water.
BN indicates bombesin.
Three bombesin receptors are currently known,.
Nonspecific binding was defined by 1 µM bombesin.
Bombesin was added to the cells at a final concentration of 1µM.
Alternatively, the peptide moiety is bombesin or a derivative, fragment or analog thereof.
A bombesin antagonist peptide having the formula, wherein.
Four infants were biopsied ; histopatological specimens were stained with bombesin antibody.
Bombesin peptide family such as neuromedin b ( nb ) are involved in the control of energy metabolism.
Peptide derivatives useful as antagonists of bombesin and gastrin-releasing peptide.
Preferably, the bombesin analog peptide antagonist sequence is selected from the group comprising,.
At one extreme, only plasmid coding for bombesin receptor is present.
Consequently, antagonists to bombesin have been proposed as agents for the treatment of these cancers.
In still other preferred embodiments, the peptide moiety is bombesin or an analog of bombesin.
In this example using the bombesin receptor, two sets of plasmids are utilized.
The peptide derivative of claim 1, wherein said peptide moiety is bombesin or an analog thereof.
Similarly, the purified bombesin analog described above was tested in a bombesin binding assay.
These peptides possess antagonist properties against bombesin or bombesin-like peptides.
Bombesin is also a tumor marker for small cell carcinoma of lung, gastric cancer, and neuroblastoma.
The isolated ileum was stimulated six times with arterial bombesin ( indicated as vertical dashed lines ).
Antibody 1E8 recognizes the part that is cleaved following stimulation with bombesin.
