Examples of 'calcineurin' in a sentence
Meaning of "calcineurin"
Calcineurin is a type of protein that plays a role in intracellular signaling. It is particularly important in the immune system and the brain.
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- A protein phosphatase that stimulates the growth and differentiation of T cells
How to use "calcineurin" in a sentence
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calcineurin
No change in calcineurin activity was observed as a result of phosphorylation.
It is a macrolide lactone and acts by inhibiting calcineurin.
The calcineurin inhibitors were cyclosporin or tacrolimus.
Induction of cardiac hypertrophy in vivo by activated calcineurin.
It also reversibly inhibits calcineurin and binds to calmodulin.
The calcineurin inhibitor may be voclosporin.
These are often used in addition to calcineurin inhibitors.
Inhibition of calcineurin activity was reported to produce analogous effects.
Increased calcium also activates calcineurin and CaMKII.
Calcineurin transgenic mice were also highly susceptible to sudden death.
It belongs to the class of calcineurin inhibitors.
Activation of the molecular response to hypertrophy in vivo by calcineurin.
Method for measuring calcineurin activity.
Another drug resistance gene is the mutant form of calcineurin.
Transgenic mice expressing calcineurin in the heart were created as follows.
See also
The remaining phosphatase activity was taken as calcineurin activity.
Using a calcineurin antagonist.
They were randomized for conversion to everolimus or maintenance of calcineurin inhibitor.
Calcineurin inhibitors can cause glomerular thrombosis and tubular injury.
Tacrolimus is a macrolide calcineurin inhibitor.
Role of calcineurin and its signaling modulators on the dystrophic phenotype.
Counter screening strains were devised for identifying calcineurin inhibitors.
The motif binds to calcineurin and inhibits its phosphatase activity.
The protein is called calcineurin.
This observation suggests that calcineurin may be regulated by protein phosphorylation.
Immunosuppressant drugs are also called immunomodulating drugs or calcineurin inhibitors.
Calcineurin activity was referenced to the assay lacking the test compounds.
No zones are seen with calcineurin inhibitors using this pair of strains.
Calcineurin is recognized to be a principal signaling molecule that regulates immune responsiveness.
Peptide mapping revealed that two major sites on calcineurin were phosphorylated.
Calcineurin is required for tolerating the membrane stress exerted by azole drugs.
Cases of lymphoma have been reported in patients treated with calcineurin inhibitors.
Tacrolimus and pimecrolimus are both calcineurin inhibitors and function as immunosuppressants.
Enzymes which are involved in a response to a hypertrophic signal in cardiomyocytes are forms of calcineurin.
A previous study demonstrated that calcineurin preparations contain variable amounts of endogenous phosphate.
Tacrolimus is a macrolide immunosuppressant belonging to the pharmacological class of the calcineurin inhibitors.
You may need calcineurin inhibitors to suppress your immune system or even antidepressants.
It has been demonstrated the neuroprotective role of cyclosporin a via calcineurin dependent or independent.
Calcineurin inhibitors has been associated with an increased risk of developing lymphomas and skin malignancies.
Some immunosuppressant drugs can also be called immunomodulating drugs or calcineurin inhibitors.
Some studies have shown that inhibition of calcineurin directly affects the proliferation of keratinocytes.
These drugs belong to a class of immune suppressant drugs known as calcineurin inhibitors.
The limiting factor in using calcineurin inhibitors is the acute and chronic irreversible nephrotoxicity.
Lymphoma is a recognised and listed adverse effect for systemically administered calcineurin inhibitor products.
The chief advantage sirolimus has over calcineurin inhibitors is its low toxicity toward kidneys.
Calcineurin inhibitors directly increase products of oxidative stress which produces swelling and endothelial dysfunction.
There is also evidence for the effectiveness of calcineurin inhibitors and lithium salt treatment.
Identified calcineurin as a potential target for LGMD therapeutics.
They are used early after transplantation along with calcineurin inhibitors and antiproliferative agents.
Cyclosporine is a calcineurin inhibitor with properties able to inhibit HIV replication.
