Examples of 'camptothecin' in a sentence
Meaning of "camptothecin"
camptothecin (adverb) - 'Camptothecin' is a naturally occurring alkaloid compound that exhibits antitumor activity. It is used in the development of chemotherapy drugs
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- An alkaloid, derived from the tree Camptotheca acuminata, that inhibits DNA topomerase and is used as an anticancer drug
How to use "camptothecin" in a sentence
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camptothecin
A number of new camptothecin derivatives have been obtained.
Stereoselective process and crystalline forms of a camptothecin.
Camptothecin has some problems in use as a drug.
Topoisomerage inhibitors such as camptothecin and topotecan.
Camptothecin compounds include irinotecan and topotecan.
Bark was significantly higher in camptothecin concentration than wood.
Camptothecin induces a reduction in cell viability.
The structure of the camptothecin prodrug is shown above.
Camptothecin agents are typically actively loaded.
As positive control camptothecin was carried along.
Camptothecin derivatives and process for preparing same.
Topotecan is an example of a camptothecin other chemotherapeuric agents include.
Protocols for systemic and local delivery of camptothecin.
Preparation of a camptothecin derivative by intramolecular cyclisation.
More specifically the active agent is a camptothecin derivative.
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The lactone camptothecin molecule is not stable in human.
A number of syntheses for camptothecin are known.
No camptothecin was detected in zero time cultures or in uninoculated culture broth.
As positive control camptothecin was used.
Camptothecin itself is insoluble in water.
The recombinant protein and camptothecin are diluted by phosphate buffer.
Camptothecin is an anticancer drug that may function as a topoisomerase inhibitor.
The present invention relates to the preparation of camptothecin derivatives.
Antioxidant camptothecin derivatives and antioxidant antineoplastic nanospheres thereof.
Topotecan is a semisynthetic derivative of camptothecin.
Camptothecin causes apoptotic death of rat cerebral cortical neurons.
Topotecan is a compound of the water soluble camptothecin analog class.
A camptothecin derivative is obtained from any chemical derivatization of camptothecin.
This route is limited because it requires an existing camptothecin to start.
Systemic delivery of camptothecin did not increase survival relative to controls.
Irinotecan is a derivative of camptothecin.
Camptothecin is conjugated in a similar manner.
The serious drawback of camptothecin is its very limited water solubility.
Camptothecin was identified by physicochemical analysis and further confirmed by spectroscopic studies.
Method of synthesizing key intermediates for the production of camptothecin derivatives.
Camptothecin completely inhibited intimal hyperplasia in the two animals tested.
A preferred active agent is one belonging to the camptothecin family of molecules.
Preferred camptothecin analogs according to the invention are irinotecan and topotecan.
A number of different reactions are reported in literature for preparing camptothecin esters.
Some camptothecin analog compounds having antitumor activities are also known.
It is known that the administration of camptothecin derivatives causes many side effects.
Camptothecin was extremely potent in its cytotoxic action against LNCaP cells.
The incomplete formation of the camptothecin salt provides a convenient purification method.
Camptothecin is also released quickly when it encounters cellular enzymes called esterases.
The availability of natural camptothecin may also limit the production of irinotecan.
Camptothecin is one cytotoxic agent that can be conjugated using these linkers.
Several methods for the synthesis of camptothecin and camptothecin analogs are known.
The new camptothecin derivatives of this invention are useful as medicaments or intermediates therefore.
Of particular interest is the combination of irinotecan or other camptothecin derivatives with cisplatin.
It is a camptothecin analogue.
