Examples of 'cancer stem cell' in a sentence
Meaning of "cancer stem cell"
Cancer stem cells are a small population of cells within a tumor that have the ability to self-renew and give rise to different types of cancer cells. They are thought to play a major role in tumor initiation, progression, and resistance to treatment.
How to use "cancer stem cell" in a sentence
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cancer stem cell
Molecular marker for cancer stem cell.
Cancer stem cell molecular markers verified in vivo.
We are now able to identify the cancer stem cell.
The cancer stem cell model.
Antagonists include soluble receptor proteins comprising cancer stem cell markers.
Cancer stem cell theory.
Any known or later developed cancer stem cell therapy may be used.
The cancer stem cell hypothesis does not contradict earlier concepts of carcinogenesis.
More evidence that melanoma does not conform to cancer stem cell model.
The cancer stem cell is one of the cell groups constituting tumor.
In a preferred embodiment of the invention said cell is a prostate cancer stem cell.
These are the cancer stem cell model and the clonal evolution model.
Genes associated with inflammation were prominent in the cancer stem cell expression profile.
Expression of a cancer stem cell marker can be determined by detection of the corresponding polypeptide.
Another stem cell that has been studied recently is the cancer stem cell.
See also
The monoclanal antibody against a cancer stem cell marker may be a humanized antibody.
The present invention provides isolated antibodies against a cancer stem cell marker.
The antagonist is a soluble cancer stem cell protein receptor or soluble receptor protein.
The antagonist is an antibody that specifically recognizes an epitope of a cancer stem cell marker.
Targeting cancer stem cell niches may represent a new opportunity for treating cancer.
The following table summarises examples of known cancer stem cell surface phenotypes.
Antagonists of a cancer stem cell marker may trigger cell death indirectly by inhibiting angiogenesis.
Any assay known in the art can be used to measure cancer stem cell growth.
A kit comprises a purified cancer stem cell marker soluble receptor in one or more containers.
A prognosis can be based on any known risk expression of a cancer stem cell marker indicates.
The presence of cancer stem cell marker expression can first be determined from a tumor biopsy.
This disclosure also encompasses bispecific antibodies that specifically recognize a cancer stem cell marker.
In an embodiment, the second cancer stem cell inhibitor is lapatinib.
This invention also encompasses bispecific antibodies that specifically recognize a cancer stem cell marker.
As a result, both regular cells and cancer stem cell abundance increases rapidly.
The present invention provides a method of identifying a drug candidate capable of inhibiting a cancer stem cell.
Without being bound by theory, a cancer stem cell can have a variety of cellular properties.
A biopsy from a patient is then analyzed for the presence of a cancer stem cell gene signature.
A list of cancer stem cell researchers can be found in Appendix 3b.
This invention also encompasses bispecific antibodies that specifically recognize cancer stem cell markers.
In certain embodiments, antibodies against a cancer stem cell marker can trigger cell death inhibiting angiogenesis.
In some embodiments, the tumor cells include a cancer stem cell.
Exemplary cancer stem cell surface antigens are listed above in Table 2.
There are several reasons why many researchers find the cancer stem cell hypothesis appealing.
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor.
In certain embodiments, the tumor cells include a cancer stem cell.
Figure 5 shows that Stat3 knockdown in cancer stem cells inhibits cancer stem cell spherogenesis.
In some aspects, the antigens are expressed on a breast cancer stem cell.
Presence of cancer stem cell ( CSCs ) is thought to mediate such resistance.
Novel stat3 pathway inhibitors and cancer stem cell inhibitors.
The cancer stem cell frequency is then calculated using L-CalcTM software ( StemCell Technologies Inc. ).
In a specific embodiment, the agent binds specifically to a cancer stem cell antigen.
For example, a leukemia cancer stem cell differentially expresses CD123 relative to a normal hematopoietic stem cell.
Fang et al . isolated a subpopulation of cells from melanoma with cancer stem cell properties.
Reduction of breast cancer stem cell frequency by anti-FZD mAb18R5.
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