Examples of 'candidate agent' in a sentence
Meaning of "candidate agent"
Candidate agent - This phrase is often used in discussions related to potential choices or individuals being considered for a particular role or position
How to use "candidate agent" in a sentence
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candidate agent
In one example the candidate agent is labeled.
Identifying a structure or sequence of the candidate agent.
In an embodiment the candidate agent is a peptide.
A candidate agent can be the only substance assayed by the method described herein.
The assay mixture also comprises a candidate agent.
The activity of the candidate agent can be assessed in a variety of ways.
Fluorescence polarization is preferable when the candidate agent is a small molecule.
Testing whether the candidate agent is able to modulate the activity of said polypeptide.
Differences between treated and untreated cells indicate effects attributable to the candidate agent.
Measuring the ability of the candidate agent to modulate the kinase activity of the polypeptide.
The experiment preferably includes a control sample which does not receive the candidate agent.
The method can identify a candidate agent which achieves a response in such a patient or test system.
The retroviruses may include inducible and constitutive promoters for the expression of the candidate agent.
In one embodiment, the candidate agent is labeled.
The in vitro culture is contacted with EGF and with a candidate agent.
See also
In some embodiments, the candidate agent is labeled.
Thereby a candidate agent binding to an AceCS2 polypeptide is identified.
Yet another embodiment is a method for identifying a candidate agent for treating NSCLC.
Thereby a candidate agent modulating an enzymatic activity of an AceCS2 polypeptide is identified.
Determining the anti-lipolytic activity of the candidate agent.
In certain aspects, the candidate agent is a wnt pathway antagonist.
In an example the competitor is added first, followed by the candidate agent.
In another embodiment, a candidate agent derived by the method is provided.
Most preferably, further assays are performed to identify the candidate agent as an antagonist.
In one example, the candidate agent causes increases glucose uptake.
Within one embodiment, the method further comprises isolating the candidate agent.
In accordance with this embodiment, the candidate agent or a control agent is administered e . g.
Optionally, this method comprises the step of identifying a structure or sequence of the candidate agent.
Accordingly, in this embodiment, the candidate agent is operably linked to a detectable molecule.
For example, a culture of the cells may be incubated with a preparation containing the candidate agent.
Similarly, the candidate agent preferably suppresses a severe cellular proliferation phenotype.
Determining the insulin-sensitising activity of the candidate agent compared with untreated adipocytes.
Selecting a candidate agent which is synthetically lethal in the first cell line ; and.
The method of claim 11 further comprising isolating the candidate agent.
In certain embodiments, the candidate agent may be an antagonist that affects such pathway.
In one example, the competitor is added first, followed by the candidate agent.
The method of claim 4, wherein the candidate agent is obtained from a library of compounds.
From the readings obtained, a pIC50 figure can be calculated for each candidate agent or compound.
Alternatively, the candidate agent is bound to the support and the protein is added.
CD95 or a functional fragment thereof a candidate agent.
In a preferred embodiment, the candidate agent can alter a flow of calcium into a cancerous cell.
Thereby a candidate agent increasing deacetylase activity of a SIRT3 polypeptide is identified.
The cells are incubated with the candidate agent for about 30 minutes and lysed.
Preferably the candidate agent inhibits the activity of the SC6 polypeptide.
The method may further comprise identifying candidate agent that increase PD-L1 expression or protein activity.
Preferably, the candidate agent inhibits expression or activity levels of an SC6 polypeptide.
Alternatively, a MIP-4 polypeptide may be administered to a candidate agent pre-bound to an immobilized CCRL2 polypeptide.
Preferably, the candidate agent selectively inhibits a CRAC channel or STIM protein.
In one preferred embodiment, the candidate agent may be a mimetic of a B-D-xyloside.
A method of identifying a candidate agent for the treatment of a behavioral disorder, the method comprising.
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