Examples of 'carbonyldiimidazole' in a sentence
Meaning of "carbonyldiimidazole"
Carbonyldiimidazole is a compound used in organic chemistry as an efficient peptide coupling reagent. It is characterized by containing carbonyl and imidazole moieties in its structure, hence the name
How to use "carbonyldiimidazole" in a sentence
Basic
Advanced
carbonyldiimidazole
With propiolic acid in the presence of carbonyldiimidazole.
Carbonyldiimidazole and imidazole are combined with anhydrous tetrahydrofuran.
Examples of the carbonyl source include carbonyldiimidazole or triphosgene.
Carbonyldiimidazole is preferred.
Examples thereof are carbonyldipyrazole and carbonyldiimidazole.
A molar equivalent of carbonyldiimidazole was added at room temperature and stirred.
An especially preferred reagent is carbonyldiimidazole.
Preferably carbonyldiimidazole is used.
An additional disadvantage of this approach is in the relatively high cost of carbonyldiimidazole.
Infrared spectroscopy confirmed that carbonyldiimidazole had been reacted with said beads.
Alternatively, a similar intermediate can be formed using carbonyldiimidazole.
Conditions for reaction with carbonyldiimidazole include reaction in an appropriate solvent in ambient temperature.
This objective is accomplished by limiting the amount of initial carbonyldiimidazole mediated activation.
Ring closure with carbonyldiimidazole furnishes imidazolone 8.
Typically, in step c the coupling agent is carbonyldiimidazole.
See also
By means of a carbonyldiimidazole group ;.
The dehydrating agent includes, for example, dicyclohexylcarbodiimide or carbonyldiimidazole.
Compound IV is allowed to react with carbonyldiimidazole to afford Compound II.
Alternatively, phosgene, diphosgene or triphosgene may be used in place of carbonyldiimidazole.
Stirring the product of step c with carbonyldiimidazole and dimethylformamide ; and.
A process according to claim 6 wherein the coupling agent is carbonyldiimidazole.
Reacting the polysaccharide component with carbonyldiimidazole to give a preactivated polysaccharide compound ;.
Typically, an amine is used as the amidation reagent in the presence of carbonyldiimidazole.
Alternative phosgene equivalents such as carbonyldiimidazole or disuccinimidyl-carbonate will react similarly.
Transforming of 45 into phthlascidin by reaction with phthalic anhydride in dichloromethane and carbonyldiimidazole.
Bis-trichloromethyl carbonate ( triphosgene ) and carbonyldiimidazole have been proven as particularly reactive carbonyl group transmitters.
The process according to Claim 4 wherein the ring closure is produced by the reactant carbonyldiimidazole.
Alternative phosgene equivalents such as carbonyldiimidazole ( see Figure 6 ) or disuccinimidyl carbonate will react similarly.
Useful condensing agents are e.g. carbodiimide derivatives such as dicyclohexylcarbodiimide, or carbonyldiimidazole.
Preferably, a standard procedure is the reaction with carbonyldiimidazole and an amine such as N, N - Diethylethylenediamine.
The process according to claim 19, wherein the carbonylating reagent is carbonyldiimidazole.
Oxazolidinone ring was made by using carbonyldiimidazole to give compound 11.
A process according to any of claims 8 to 12 where the activating agent is carbonyldiimidazole.
The dehydrating agent includes, for example, carbonyldiimidazole dicyclohexylcarbodiimide, and the like.
Step ( a ) is suitably carried out in the presence of a coupling agent, for example carbonyldiimidazole.
The carbonyldiimidazole method, in which an N-acylimidazole intermediate is involved, can also be used.
Derivative 9 is converted to the cyclic carbonate 10 by reaction with carbonyldiimidazole and sodium hexamethyldisilazide.
Potassium cyanide ( KCN ), Carbonyldiimidazole and involves reactions to be performed under anhydrous conditions.
Compound 6A is then treated with sodium hexamethyldisilazide and carbonyldiimidazole to give compound 6B.
Compound 2-A is reacted with carbonyldiimidazole to form Compound 2-B comprising an imidazole moiety.
The process according to claim 39, wherein the carbonylating reagent is carbonyldiimidazole or phosgene.
Of commercial carbonyldiimidazole are added to 9.6 g of commercial difluoroacetic acid in 75 ml of diglyme.
Suitable carboxylate-reactive functional groups include diazoalkanes, diazoacetyl compounds, carbonyldiimidazole compounds, and carbondiimides.
Carbonyldiimidazole ( CDI, 1 equivalent ) is then slowly added.
The carboxylic acid derivative ( II ) is dissolved in an organic solvent, and carbonyldiimidazole is added.
Method comprising using carbonyldiimidazole ( CDI ).
The IIA compound ( imidazolide ) can be obtained by reacting compound II ( non-activated ) with carbonyldiimidazole.
Coupling reagents include carbodiimides, such as DCC, DIC, EDCI or a carbonyldiimidazole such as CDI.
Suitable carboxyl-activating agents include 2-chloro-N-methyl pyridinium iodide, dicylohexylcarbodiimide and carbonyldiimidazole.
This imidazolide is obtained in a single step from maleimidocaproic acid and carbonyldiimidazole ( CDI ), STR30.
