Examples of 'caspase activation' in a sentence

Meaning of "caspase activation"

Caspase activation: A process in cell biology involving the activation of caspase enzymes that play a crucial role in apoptosis (cell death) and inflammation

How to use "caspase activation" in a sentence

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caspase activation
Caspase activation assays was carried out using cell extracts.
Both of the viral reaper preparations resulted in caspase activation.
The degree of caspase activation is directly related to the degree of apoptosis.
T4 cells did not exhibit the high level of caspase activation.
Caspase activation is a common feature of chronic toxicity and cell death.
In some embodiments, the present invention enables caspase activation.
Smac also allows caspase activation in the presence of physiological levels of potassium salt.
In other embodiments, the present invention causes cellular caspase activation.
DNA fragmentation and caspase activation were analyzed as parameters for apoptosis.
However, induction of p21 overexpression in these conditions prevented apoptosis by inhibition of proximal caspase activation.
The results demonstrate dose-dependent enhanced caspase activation with combination treatment.
Caspase activation was revealed by the hydrolysis of Ac-DEVD-amc upon incubation with liver cell extracts.
Distinctly different effect was obtained for the low dose cytochrome c-induced caspase activation.
The last caspase activation model is the association of the pro-caspase with a regulating sub-unit.
In the absence of dATP, AFP did not induce any caspase activation at all.

See also

Caspase activation is involved in Senecio-induced apoptosis.
These findings suggest that betulinic acid-induced caspase activation is mediated by mitochondrial PT.
Caspase activation was monitored by the cleavage of specific caspase-3 fluorogenic substrate DEVD-AMC.
Additionally, S1P effectively inhibits ceramide-induced apoptosis in association with decreased caspase activation.
Upstream events leading to caspase activation involve the balance between pro - and anti-apoptotic BCL-2-family proteins.
Once bound, the serine protease cleaves the LAP, reducing the cell 's inhibition to caspase activation.
The effect on caspase activation in HL-60 cells was also measured.
BCL-like proteins include BCL-xL and BAX-alpha, which appear to function upstream of caspase activation.
Figure 12, Caspase activation on LNCaP prostate cancer cell lines.
Panel b, FTY720 induced apoptosis is dependent on caspase activation.
Figure 3B shows caspase activation by the anti-Notch4 antibody.
Figure 13, FTY720 induced apoptosis in Mantle cell lymphoma cells through caspase activation dependent mechanism.
FIG . 12, Time course of caspase activation on LNCaP prostate cancer cell lines.
Fig 4 . FTY720 induced cytotoxicity in CLL cells is independent of caspase activation.
Taxol-induced caspase activation was enhanced by the addition of LT3000 to the culture medium.
Binding soluble TRAIL to DR4 or DR5 leads to to caspase activation and apoptosis [ 6 ].
This caspase activation was not blocked by antioxidants or inhibition of polyamine oxidase by MDL 72527.
FIG . 12, Caspase activation on LNCaP prostate cancer cell lines.

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Examples of using Caspase
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