Examples of 'cell binding agent' in a sentence
Meaning of "cell binding agent"
cell binding agent: A substance that helps cells stick together or to other surfaces, commonly used in cell biology and biotechnology
How to use "cell binding agent" in a sentence
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cell binding agent
The cell binding agent is preferably an antibody.
The preferred ratios of pyrrolobenzodiazepine to cell binding agent are given above.
The cell binding agent may be antibody.
Any suitable antibody can be used as the cell binding agent.
In another embodiment, the cell binding agent may be labelled with a radioisotope.
The capping group is intended not to be reactive towards a cell binding agent.
Preferably the drug is linked to a cell binding agent through a disulfide bond.
Compound A comprises this PBD with a linker for attachment to a cell binding agent.
L and G L is a linker connected to the cell binding agent in the conjugate compound.
In some embodiments, there is one dimer pyrrolobenzodiazepine group per cell binding agent.
According to a preferred aspect, the cell binding agent is an antibody, in particular a monoclonal antibody.
A conjugate of formula ConjB, where CBA represents a cell binding agent.
In one embodiment the cell binding agent comprises a peptide that binds integrin avB6.
Alternatively an antibody specific to the cell binding agent may be used.
The Cell Binding Agent also may be antibody or an antigen-binding fragment of an antibody.
See also
The method according to claim 1, wherein said cell binding agent is a monoclonal antibody.
The cell binding agent may be, or comprise, a polypeptide.
The method according to claim 1, wherein said cell binding agent is an antibody fragment.
A cell binding agent may be of any kind, and include peptides and non-peptides.
Preferably, a humanized anti-EphA antibody is used as the cell binding agent of the present invention.
Such a Cell Binding Agent can be a protein, polypeptide, peptide or a non-peptidic agent.
Or ConjB, where CBA represents a cell binding agent.
In some embodiments, the Cell Binding Agent may be a protein, polypeptide or peptide.
A conjugate of formula ConjA, ConjA where CBA represents a cell binding agent.
In some embodiments, the Cell Binding Agent may be a cyclic polypeptide.
In this embodiment, the S atom is typically derived from the cell binding agent.
In one embodiment the cell binding agent comprises the A20FMDV-Cys polypeptide.
In one embodiment, the Linker-Drug compounds are designed for connection to a Cell Binding Agent.
Thus, L1 and the cell binding agent are directly connected.
The cytotoxic agent of paragraph 1 or 2, wherein said cell binding agent is a growth factor.
Thus, L1 and the cell binding agent are indirectly connected.
Preferably, a humanized anti-CD38 antibody is used as the cell binding agent.
The cell binding agent is an antibody ( e.g., monoclonal antibodies and fragments thereof ).
Preferably, a humanized anti-EphA2 antibody is used as the cell binding agent of the present specification.
Preferably, a humanized anti-CD38 antibody is used as the cell binding agent of the present invention.
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