Examples of 'cerivastatin' in a sentence
Meaning of "cerivastatin"
Cerivastatin is a noun that denotes a synthetic compound or drug, often used in pharmacology or medical contexts
Show more definitions
- A synthetic statin formerly used to lower cholesterol and prevent cardiovascular disease, later withdrawn due to the risk of rhabdomyolysis.
How to use "cerivastatin" in a sentence
Basic
Advanced
cerivastatin
Cerivastatin is metabolized via the hepatic pathway.
Interaction between cerivastatin and clopidogrel.
Cerivastatin is exclusively cleared by hepatic metabolism.
No such data exist for cerivastatin.
Cerivastatin consists of a fluorophenyl linked to a pyridine.
Additional known statins include cerivastatin and mevastatin.
This study was stopped following the suspension of marketing and distribution of cerivastatin.
The Committee agreed that cerivastatin containing medicinal products are effective in the treatment of.
No deaths were reported among the patients treated with cerivastatin.
Exposure Data Data suggest that cerivastatin is used much less frequently than the other statins.
The lack of predictability of potential drug interactions with cerivastatin has.
Cerivastatin was generally found to be well tolerated, side effects being rare.
The risk of rhabdomyolysis is greatly increased when cerivastatin is used concomitantly with.
The lipophilic cerivastatin has a pyridine-based ring structure.
Data from pharmacoepidemiological studies do not support an increased risk with cerivastatin monotherapy.
See also
Figure 6 is a release profile of cerivastatin released from a stent coating of polycaprolactone film.
The Committee agreed that there were concerns related to the safety profile of cerivastatin containing.
Figure 7 is a release profile of cerivastatin released from a stent coated with silicone.
The CPMP has recommended the withdrawal of the Marketing Authorisations for cerivastatin.
Figure 8 is a release profile of cerivastatin released from a stent coated with liquid vitamin.
Wherein said HMG-CoA reductase inhibitor is cerivastatin.
Cerivastatin revealed an increasing reporting rate of rhabdomyolysis especially when co-administrated with gemfibrozil ( a fibrate ).
When exposure data are considered, the reporting rate is considerably higher with cerivastatin.
Figure 5 is a release profile of cerivastatin released from a stent coating of EVA film.
There is convincing evidence that the risk of rhabdomyolysis with cerivastatin is dose-dependent.
Four mg of cerivastatin was dissolved in 100 µl of methylene chloride.
When used concomitantly, nifedipine does not affect the pharmacokinetics of candesartancilexetil, cerivastatin or irbesartan.
For example, cerivastatin has anti-thrombotic activity.
In a preferred embodiment, the HMG-CoA reductase inhibitor used in the coating composition is cerivastatin.
Three mg of cerivastatin was dissolved in 300 µl of methylene chloride at room temperature.
Collected samples were assayed for the spectral characteristics of cerivastatin using a UV-VIS spectrophotometer.
Cerivastatin was voluntarily withdrawn from the market worldwide in 2001, due to reports of fatal rhabdomyolysis.
A similar result has previously been obtained for another statin, cerivastatin Ando, Takamura et al.
At 60 % the bioavailability of cerivastatin is greater than that of any of the other statins.
Pre-clinical Data Toxicology data confirmed the myotoxicity of cerivastatin.
Incidence of rhabdomyolysis with cerivastatin 0.4mg is 2 fold greater than with other statins.
More preferably, the HMG-CoA reductase inhibitor is cerivastatin.
Examples of the antihyperlipidemic agents include cerivastatin sodium, simvastatin, pravastatin sodium, etc.
Particular hypolipidemic agents are pravastatin, simvastatin, lovastatin, atorvastatin, fluvastatin or cerivastatin.
Figure 4 is a UV-VIS spectra of cerivastatin released from a stent coating.
The preferred hypolipidemic agent is pravastatin, simvastatin, lovastatin, atorvastatin, fluvastatin or cerivastatin.
Cerivastatin effectively and dose-dependently reduces total cholesterol, LDL - cholesterol, triglycerides and apolipoprotein B and increases HDL-cholesterol.
By this method, a diffusion-based release system for cerivastatin was created.
Baycol, cerivastatin sodium tablets [ product monograph ].
Preferred hypolipidemic agents are pravastatin, lovastatin, simvastatin, atorvastatin, fluvastatin and cerivastatin.
Cerivastatin ( baycol ® ) and gemfibrozil - increased risk of rhabdomyolysis - concomitant use contraindicated.
Currently available statins include lovastatin, simvastatin, pravastatin, fluvastatin, cerivastatin and atorvastatin.
Example 5 . A 10 % w / w solution of cerivastatin in vitamin E was created by the following method.
The Committee, based on present evidence, considered the risk / benefit balance of cerivastatin.
The other statins are lovastatin, pravastatin, simvastatin, cerivastatin ( now off market ), fluvastatin and atorvastatin.