Examples of 'chain gene' in a sentence
Meaning of "chain gene"
chain gene - This phrase could have multiple interpretations depending on the context. It could refer to the genetic inheritance of a particular trait within a family lineage, or it could allude to a sequence of links or connections in a chain-like manner
How to use "chain gene" in a sentence
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chain gene
Heavy chain gene construction.
Primers containing the desired mutations were used to amplify regions of the heavy chain gene.
The rearranged heavy chain gene is somewhat more complex.
Transformed plants containing the truncated ricin A chain gene were recovered.
The light chain gene was synthesized from these olignucleotides in two parts.
The correct orientation of the light chain gene was verified by restriction analysis.
In one embodiment, the mouse comprises a functional light chain gene.
The use of a particular heavy chain gene segment defines the class of immunoglobulin.
Preferably, the target locus encodes an antibody heavy chain gene.
Variable heavy chain or variable light chain gene constructs are subcloned into appropriate expression vectors.
Thus, a constant region of the antibody light chain gene was obtained.
Other DJH rearranged IgH chain gene loci can be targeted with the same targeting vector.
K, λ light chain usage of mice bearing human λ light chain gene segments.
In one aspect, the light chain gene segments are human k light chain gene segments.
In a specific aspect, the immunoglobulin gene segments are light chain gene segments of another species.
See also
However, the Yl chain gene is preferred if a higher complement-activating effect and ADCC are desired.
The procedure for cloning the expressed light chain gene is outlined in part B below.
A suitable vector is readily constructed from the above-described vectors by excising the a chain gene.
Therefore, the foregoing humanized light chain gene was reconstructed to introduce mutations at these positions.
In a specific embodiment, the two human immunoglobulin gene segments are heavy chain gene segments.
This probe should react with e chain gene of both the secreted and membrane-bound forms.
In a specific embodiment, the variable region nucleic acid sequences comprise immunoglobulin heavy chain gene segments.
The sequences of the heavy chain gene with stuffers is depicted in Table 6.
SP2/O myeloma cells were transfected with the different heavy and light chain gene constructs.
The sequence of the lambda light chain gene with stuffers is depicted in Table 11.
The JH6 primers is used as a positive internal control for the immunoglobulin heavy chain gene.
This is a schematic representation of the human heavy chain gene complex, not shown to scale.
Light chain gene copy numbers and hCMV-MIE methylation of antibody producing CHO cell lines.
Figure 8 shows Northern blot analysis of a chain gene transformants.
The prepared I chain gene fragment was cloned into an expression vector, pUCAG.
Example 1, preparation of toxin gene Site directed mutagenesis of ricin toxin B chain gene.
The sequences of the kappa light chain gene with stuffers is depicted in Table 10.
Example 4 This example describes mutagenesis of the Fc region of the human Y1 heavy chain gene.
CDR-grafted light chain gene construction.
H represents an anti-CD2 antibody heavy chain gene.
Figure 14 Light chain gene copy numbers before and after stability testing without MTX.
Transfecting the culture with an expressible Class I MHC heavy chain gene operably linked to a promoter ;.
The alpha chain gene contains 5 exons.
I represents an anti-CD2 antibody light chain gene.
However, in case of the IgH chain gene locus, another method can be applied,.
The first discovery of a eukaryotic enhancer was in the immunoglobulin heavy chain gene in 1983.
There is one beta chain gene on each 11th chromosome, for a total of two.
Figure 10 shows Western blot analysis of a chain gene transformants.
The CD4-gamma2 chimeric heavy chain gene was subcloned into the mammalian expression vector pcDNA1.
FIGURE 4 shows a vector for the expression of chimeric or humanized MN-14 kappa chain gene.
The HCMV promoter lies 5 ' to the heavy chain gene and directs its transcription.
Furthermore, less than 5 % of murine B cells express λL chain gene loci.
The immunoglobulin heavy chain gene of pGl-Neo comprises a mouse / human chimeric immunoglobulin gene ( Figure 9 ).
The VI was generated by site directed mutagenesis of the humanized 1308F light chain gene.
The prepared H chain gene fragment was cloned into an expression vector, pCXND3.
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