Examples of 'class i molecules' in a sentence
Meaning of "class i molecules"
class i molecules - specific proteins found on the surface of cells that play a key role in the immune system
How to use "class i molecules" in a sentence
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class i molecules
The method utilizes purified class I molecules and radiolabeled synthetic probes based on consensus peptides.
These cells are defective in intracellular peptide loading of class I molecules.
Class I molecules bind peptides in a specific manner.
The overall structure of FcRn is similar to that of class I molecules.
All nucleated cells express class I molecules on their cell surface.
HLA class I molecules are expressed on the surfaces of all nuclear cells in a body.
Tumor antigens are presented on MHC class I molecules in a similar way to viral antigens.
HLA class I molecules are expressed on the surfaces of all nucleated cells in a body.
This results in a reduction of HLA class I molecules containing labelled indicator peptides.
Later on the peptides are presented on the surface in association with MHC class I molecules.
Radioactively labelled MHC class I molecules are not necessarily required to measure peptide binding.
These observations are consistent with the characteristics of empty Class I molecules mentioned above.
Test peptides which bind to HLA class I molecules successfully inhibit binding of indicator peptides.
It is preferable that the host cell expresses substantially no MHC class I molecules before transfection.
All MHC class I molecules isolated from PBMCs have endogenous peptides bound to them.
See also
Evidence for functionally unique monomorphic determinants on class I molecules has recently been published.
MHC Class I molecules bind peptides having particular amino acid motifs well known in the art.
Cells are not the only source of HLA class I molecules for binding assays.
Conveniently said host cell before transfection expresses substantially no MHC class I molecules.
Infected nucleated cells will present MHC Class I molecules on their cell surface.
This bank of CTL clones is available for patients expressing the appropriate HLA class I molecules.
All peptides examined to date that bind to class I molecules contain a carboxyl-terminal anchor.
The most important ligands for inhibitory receptors are MHC class I molecules.
All HLA class I molecules were highly up-regulated in mDC as compared with iDC.
Antibodies specific for conformationally correctly folded HLA class I molecules are used for immunoprecipitation.
In addition, MHC class I molecules presenting self peptides are expressed on the cell surface.
All normal cells in the body express the MHC class I molecules on their surface.
As a result, the class I molecules appear on the Drosophila cell surface as empty vessels.
Essentially all nucleated cells have class I molecules.
Major histocompatibility complex ( MHC ) class I molecules are expressed on the surface of nearly all cells.
This results in antigen binding to MHC class I molecules.
In this respect, Class I molecules display some resemblance to antibodies.
Assembly assay for peptide binding to MHC class I molecules.
A variety of MHC class I molecules have been identified and well-known.
Peptides are selected that are capable of binding to the empty MHC Class I molecules.
Furthermore, BGs enhanced expression of MHC class I molecules and co-stimulatory molecules on DCs.
LLO is very efficiently presented to the immune system vía MHC class I molecules.
Various MHC class I molecules have been identified and are well-known.
The host cell preferably expresses substantially no MHC class I molecules before transfection.
Class I molecules were then immunoprecipitated from the lysates and analyzed by SDS-PAGE.
Antigenic peptide presentation in association with MHC class I molecules leads to CTL activation.
These two class I molecules have many similarities in structure and share similar binding motifs ( 19 ).
In another aspect, the peptides bind to three distinct HLA class I molecules.
A new foreign policy, MHC class I molecules monitor the outside world.
However, some pathogens also succeed in reducing the class I molecules of MHC.
Class I molecules are composed of a heavy chain in complex with β2-microglobulin.
In another embodiment, the peptides bind to five distinct HLA class I molecules.
MHC class I molecules are heterodimers that consist of two polypeptide chains, α and β2-microglobulin b2m.
In another aspect, each of the peptides binds to a distinct set of HLA class I molecules.
Peptide ligands eluted from MHC class I molecules are relatively short, ranging from 8 to 11 amino acids.
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