Examples of 'classical pathway' in a sentence
Meaning of "classical pathway"
classical pathway - This phrase is often used in biology or medicine to describe a standard or well-established sequence of reactions or processes within a biological system
How to use "classical pathway" in a sentence
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classical pathway
The classical pathway for complement activation is initiated by.
Antibodies can stimulate the classical pathway of complement activation.
The classical pathway is triggered by an antibody bound to the target antigen.
Activators of the classical pathway.
The classical pathway is usually triggered by an antibody bound to a foreign particle.
Activation of classical pathway.
The classical pathway is so called because it was the first one identified.
The assay is designed to be specific for the classical pathway of complement activation.
The classical pathway is initiated by the binding of antibodies to cell surface antigens.
The complement cascade progresses vÃa the classical pathway or the alternative pathway.
Thus, immunoglobulin in the form of immune complexes can trigger the classical pathway.
Initiation of the classical pathway begins with antibody binding to a specific antigen.
Binding of antibodies to red blood cells activates the classical pathway of the complement system.
The classical pathway is primarily activated by immune complexes, specifically IgG / IgM antibodies bound to antigen.
The assay procedures are similar to those of the classical pathway hemolysis assay described above.
See also
In yet another embodiment, the disorder is associated with the complement classical pathway.
It has been speculated that the classical pathway emerged evolutionarily after the lectin pathway.
For example, of the human antibodies, IgM and IgG activate the classical pathway.
IgG activates the classical pathway of the complement system.
In another embodiment, the complement pathway is a classical pathway of complement.
A classical pathway in excellent houses, then two years in Polynesia.
The data shows the Polar Assortant peptide regulating classical pathway activation in a dose dependent manner.
For example, as described above, the binding of antibody to antigen initiates the classical pathway.
C1q is the first component of the classical pathway of the complement system.
Thus, activation of the complement cascade after nerve crush occurs through the classical pathway.
C4BP is a regulatory protein of the classical pathway of the complement system.
C3b deposition monitored using this method is generated through complement activated by the classical pathway.
The protocol for the classical pathway activation assay is described in Example 1.
Table 2 summarizes the ways in which the classical pathway is regulated.
The Classical Pathway, The classical pathway mediates specific antibody responses.
There are two pathways for activating complement, the classical pathway and the alternate pathway.
C3b originates from classical pathway activation and / or from natural spontaneous hydrolysis of C3.
Circulating IgMs appear to recognize the new determinant, bind and activate classical pathway of complement.
The classical pathway is inhibited by C1-inhibitor, which binds to C1 to prevent its activation.
Its function is homologous to that of C1s in the classical pathway.
FIG . 4 shows examples of classical pathway hemolytic assays with 20 % human serum.
This prevents formation of the enzyme C3 convertase, thus stopping the classical pathway cascade.
FIG . 8 shows examples of classical pathway hemolytic assays ( 5 % cynomolgus serum ) with matrured Fabs.
The alternative complement pathway involves an amplification loop utilizing C3b produced by the classical pathway.
The recruitment of the complement cascade via the classical pathway ( antibody-antigen interaction ).
The complement cleavage product C4d is a marker for activation of the antibody-dependent classical pathway.
FIG . 13 shows characterization of germlined IgGs in classical pathway hemolytic assay using 5 % cynomolgus serum.
CCP2 and CCP3 alone are involved in its inhibition of the classical pathway.
These results demonstrate that the classical pathway is intact in the MASP-2 - / - mouse strain.
The Lectin Pathway, The lectin pathway is similar to the classical pathway.
In the classical pathway of complement activation, the complex C4b, 2a is the C3 convertase.
Methods, Effects of the lectin pathway and the classical pathway on C3 deposition.
The classical pathway is initiated when complement factor 1 ( C1 ) recognises surface-bound immunoglobulin.
All anti-C2a MAbs strongly inhibit classical pathway hemolysis.
Following the activation of C4 and C2, the lectin pathway is identical to the classical pathway.
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