Examples of 'clavulanate' in a sentence
Meaning of "clavulanate"
Clavulanate is an adjective used in medicine to describe a type of antibiotic often combined with amoxicillin
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- Any salt or ester of clavulanic acid.
How to use "clavulanate" in a sentence
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clavulanate
Clavulanate is preferably in the form of potassium clavulanate.
Augmentin is a combination of amoxicillin and clavulanate potassium.
Potassium clavulanate is known to be extremely water sensitive.
Process for the preparation of potassium clavulanate.
Potassium clavulanate equivalent to clavulanic acid.
Pharmaceutical formulation containing amoxycillin and clavulanate.
If necessary potassium clavulanate can be recrystallized.
Pharmaceutical formulations comprising amoxycillin and clavulanate.
However lithium clavulanate is not a pharmaceutically acceptable salt.
It also acts as an ionic counterbalance to the clavulanate accumulating.
Potassium clavulanate is the most stable pharmaceutically acceptable derivative.
Process for crystallization of potassium clavulanate.
Commercial preparations contain potassium clavulanate in combination with amoxycillin trihydrate.
Potassium clavulanate is normally supplied in admixture with silicon dioxide as diluent.
A sufficient high bioavailability of the clavulanate is still provided.
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Potassium clavulanate is more stable than the free acid or other salts.
From the solution the metal clavulanate salt is separated.
Preferably bottles also include a desiccant material to preserve the clavulanate.
Also invented are methods of transporting clavulanate and compositions containing clavulanate.
This is particularly advantageous in allowing the required purity of potassium clavulanate to be formed.
Potassium clavulanate is obtained.
Novel method of treatment using a high dosage regimen of amoxycillin and potassium clavulanate.
A potassium clavulanate precipitate may comprise the known needle or rosette crystal forms.
Formulations comprising amoxycillin and potassium clavulanate in a range of ratios have been previously described.
The use of clavulanate in combination with amoxycillin consequently enhances the effectiveness of amoxycillin.
Commercial preparations of clavulanic acid contain potassium clavulanate in combination with amoxycillin trihydrate.
Clavulanate is a heat labile-moisture sensitive compound.
The present invention relates to a novel crystalline form of potassium clavulanate having improved properties.
Amoxycillin trihydrate and clavulanate differ substantially with respect to their solubility in water.
The other portion of Augmentin is clavulanic acid or clavulanate.
Agglomerates of potassium clavulanate of the present invention show a good level of stability and hygroscopicity.
Preferably, agglomerates of potassium clavulanate are produced.
Clavulanate works as an inhibitor of β-lactamases.
CLAVAMOX contains amoxicillin and clavulanate and is known as potentiated penicillin.
Preferably, bottles also include a desiccating material, to preserve the clavulanate.
Amoxicillin-potassium clavulanate combination.
Similar strips have been developed impregnated with cefotaxime / clavulancate or cefepime clavulanate.
The weight ratios of amoxycillin, clavulanate expressed herein are as free acid equivalent.
The conversion is made by adding for example potassium 2-ethylhexanoate and precipitating potassium clavulanate.
The t-octylamine clavulanate was subsequently isolated by filtration, and washed with ethyl acetate.
It is almost always sold and used in combination with clavulanate as ticarcillin / clavulanic acid.
Potassium clavulanate is an exceptionally difficult material to formulate, being extremely hygroscopic and moisture sensitive.
Pharmaceutically acceptable salts such as potassium clavulanate are prepared by re-salting from lithium clavulanate.
Preferably, said agglomerates comprise clavulanic acid or a pharmaceutically acceptable salt thereof like potassium clavulanate.
A drawback of the " dry syrup " powder is that the clavulanate is very sensitive to hydrolysis.
T-BA clavulanate was charged to the reactor followed by isopropanol and water.
Whereas the amount of amoxycillin may vary, the amount of clavulanate is normally fixed.
Amoxycillin and potassium clavulanate are respectively a known B-lactam antibiotic and a known B-lactamase inhibitor.
From the dehydrated, purified ethyl acetate extract the intermediate sodium clavulanate was obtained as follows,.
Further, the agglomerates comprising potassium clavulanate may contain amoxicillin as the active B-lactam antibiotic compound.
