Examples of 'clofarabine' in a sentence
Meaning of "clofarabine"
Clofarabine is a chemotherapy medication used in the treatment of certain types of cancer, particularly leukemia
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- A purine nucleoside antimetabolite used in the treatment of leukaemia.
How to use "clofarabine" in a sentence
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clofarabine
Clofarabine is predominately excreted via the kidneys.
Evoltra contains the active substance clofarabine.
Clofarabine shows high tissue distribution.
Ivozall contains the active substance clofarabine.
The metabolic pathways of clofarabine in humans were not characterized.
Clofarabine was teratogenic in rats and rabbits.
The characterization of kinetics of clofarabine in these models is limited.
Clofarabine is one of a family of medicines called cytotoxic medicines.
It contains the active substance clofarabine.
Clofarabine is one of a family of medicines called anticancer medicines.
There are no data on the use of clofarabine in pregnant women.
Clofarabine quickly kills leukaemia cells in the blood.
Method for the synthesis of clofarabine.
The excretion of clofarabine in milk has not been studied in animals.
There is no evidence that intracellular uptake of clofarabine is cell specific.
See also
Plasma clofarabine concentrations were generally maximal by the end of infusion.
No formal interaction studies have been performed to date with clofarabine.
Administration of clofarabine results in a rapid reduction in peripheral leukaemia cells.
Hepatic effects were observed in rats following chronic administration of clofarabine.
Mice were treated with clofarabine alone or clofarabine plus radiation.
The active substance is clofarabine.
Increases in exposure of clofarabine due to decreased clearance were shown with cimetidine.
Other hypomethylating agents of note include clofarabine and hydralazine.
Clofarabine is a prodrug and exerts its activity through active metabolites.
Evoltra is a cancer medicine that contains the active substance clofarabine.
It is unknown whether clofarabine or its metabolites are excreted in human breast milk.
The radiosensitizing capacity of gemcitabine tracked with the clofarabine results.
Clofarabine may affect the levels of certain substances in the blood.
Several methods for the production of clofarabine are currently established in the art.
Clofarabine should not be used during pregnancy unless clearly necessary.
The following parameters should be closely monitored in patients undergoing treatment with clofarabine.
Clofarabine may cause serious birth defects when administered during pregnancy.
Patients should be monitored for renal toxicity and clofarabine should be discontinued as necessary.
Clofarabine may cause harm to unborn babies when used by pregnant women.
The use of disposable gloves and protective garments is recommended when handling clofarabine.
The clofarabine obtained has a high purity without detectable amounts of impurities.
These cells are readily resistant to clinically relevant dose of clofarabine and harbor luciferase activity.
Clofarabine is a cytotoxic purine nucleoside analogue that primarily works by inducing apoptosis.
Men must also use effective contraception while they or their partner are treated with clofarabine.
Clofarabine was also active against quiescent lymphocytes and macrophages and proliferating lymphoblasts.
The recovery of DNA synthesis appeared to be inversely related to clofarabine dose.
Clofarabine can also cause tachycardia and can affect the liver and kidneys.
Seven patients received an HSCT after the first dose of clofarabine.
The protected clofarabine obtained may be crystallized from amixture of ethyl acetate and methanol.
What Evoltra contains The active substance is clofarabine.
Cladribine and clofarabine are two other medications being investigated in MCL.
Deprotecting the compound of formula 7 to obtain clofarabine.
Cladribine and clofarabine are two other drugs being investigated in MCL.
Difficile colitis, have been reported during treatment with clofarabine.
Clofarabine was not mutagenic when tested in the in vitro mutagenicity assay Ames test.