Examples of 'clonal expansion' in a sentence
Meaning of "clonal expansion"
clonal expansion - In biology, clonal expansion refers to the rapid multiplication of genetically identical cells derived from a single ancestral cell. This term is commonly used in discussions related to immunology, cancer research, and stem cell biology.
How to use "clonal expansion" in a sentence
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clonal expansion
Activation leads to clonal expansion and affinity maturation.
Clonal expansion leading to preneoplastic lesions.
Therefore only dramatic clonal expansion can be discerned by spectratyping.
The same stages of clonal selection and clonal expansion as.
Therefore only dramatic clonal expansion can be discerned by this technique.
Clonal expansion was expressed as a fraction of the initial viable cell number.
Promotion involving clonal expansion.
This results in a clonal expansion of promyelocytic cells and development of leukaemia.
The hallmark of the adaptive immune system is clonal expansion of lymphocytes.
This clonal expansion and differentiation showed all the cells to have ability to form neurons.
Measuring clonal expansion.
Activation of the adaptive immune cells leads to their clonal expansion.
Most neoplasms arise from the clonal expansion of a single cell that has undergone neoplastic transformation.
Progression is optionally determined by assessing the selective clonal expansion of initiated cells.
These cytokines induce clonal expansion of the T cells and activation of the cytokine network.
See also
The selection step may also be carried out after the clonal expansion.
This leads to a clonal expansion of malignant B lymphocytes.
Early gene products provide transforming proteins that ensure clonal expansion of infected cells.
Most CLL patients have clonal expansion of lymphocytes with B cell characteristics.
This response involves cells specifically recognizing the antigen and will then lead to clonal expansion.
A large number of mutants that arose through clonal expansion from a single mutation.
Preferably, clonal expansion leads to differentiation of the lymphocytes.
This interaction leads to a role in clonal expansion of T cells.
Clonal expansion and differentiation of T-cells into effector cells.
A preferred way of inducing selective clonal expansion of B cells is DNA tattoo vaccination.
Multiple myeloma ( mm ) is a cancer of plasma cells resulting from anomalous clonal expansion.
Neovascularization is a pre-requisite for clonal expansion associated with the formation of macroscopic tumors.
The method of claim 8, wherein a high clonality rating is indicative of specific clonal expansion.
After activation, they enter a quick clonal expansion phase, in which they exponentially divide.
Yet another attempt to arrive at antibody producing cells is the clonal expansion of B-cells.
Anergic T-cells do not undergo clonal expansion and / or acquire effector functions.
Preferably, the cells are cultured under conditions suitable for the clonal expansion of the B cells.
Similar to the EGF experiments, a clonal expansion of the constitutively proliferating cell population is achieved.
IL-7Ra is essential for promoting thymocyte differenciation and clonal expansion of lymphocytes.
It is required for the clonal expansion of antigen - or mitogen-activated T cells.
Exogenous LIF and addition of EGF dramatically improved clonal expansion of the vA+ cells.
Most CLL patients also have clonal expansion of lymphocytes with B-cell characteristics.
The CD45 marker is expressed on T cells that have already undergone clonal expansion.
This suggests that melatonin is involved in the clonal expansion of antigen-stimulated human T lymphocytes.
Clonal expansion together with Electrofusion offers the possibility to fuse preselected specific B-cells.
Mark Davis has developed a method to track T-cell clonal expansion in various diseases.
The clonal expansion of T cells following TCR and co-stimulatory receptor engagement requires tremendous synthetic demands.
Once this occurs, an antigen specific clonal expansion of T helper cells will take place.
The activation causes secretion of cytokines ( IL-2, IFNY ) and clonal expansion.
Immune cells, such as B cells, may undergo rapid clonal expansion upon the presence certain diseases.
It drives rapid clonal expansion of naive but not memory CD4 T-cells.
II found that cross-linking CD40 is necessary for clonal expansion of B cells.
The system also induces the clonal expansion of both antigen specific CD4 and CD8 T cells.
Banchereau et al . II found that cross-linking CD40 is necessary for clonal expansion of B cells.
T-cell lymphomas involve the clonal expansion of individual malignant T-cells.
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Clonal selection versus tissue culture production
Four predictions of the clonal selection hypothesis
Clonal selection of vines producing table grapes
Examples of using Expansion
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Expansion or contraction of oven during heating cycle
Sounds of metal expansion and contraction are normal
Expansion tank required if a backflow preventer is installed
