Examples of 'co-receptor' in a sentence
Meaning of "co-receptor"
Co-receptor is a cell surface receptor that enhances the action of the primary receptor
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- Alternative form of coreceptor
How to use "co-receptor" in a sentence
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co-receptor
The antigen may be a receptor or a co-receptor on a cell.
It is the co-receptor interaction that stimulates entry of the adenovirus.
In one embodiment of the above compositions, the co-receptor is a chemokine receptor.
Assessing co-receptor tropism is mandatory for the prescription of these drugs.
This normalizes mAb binding for mutant co-receptor expression levels.
Malfunctions in this co-receptor lead to lower bone density and strength which contribute to osteoporosis.
Phenotypic assays are usually recommended over genotypic assays to infer co-receptor tropism.
Depending on the type of ligand a co-receptor binds, its location and function can vary.
In one embodiment, the nucleotide sequence is present at an endogenous T cell co-receptor locus.
The inhibitor of an HIV co-receptor is an inhibitory nucleic acid.
It is possible that under selective pressure HIV will evolve to use another co-receptor.
Inferring therefrom whether the virus uses a cell co-receptor expressed by the test cell, or not.
As with chemokine co-receptor antagonists, they are rarely used in the United States.
In certain embodiments, the inhibitor of an HIV co-receptor is an inhibitory nucleic acid.
The T-cell co-receptor is a protein complex and is composed of four distinct chains.
See also
In some embodiments, ligand binding molecule includes a co-receptor and a VEGFR fragment.
Deactivation of a specific T cell co-receptor as a result of positive selection is a product of transcriptional regulation.
An object of the present invention is to provide new antagonists for the CXCR4 co-receptor.
The T cell co-receptor is a protein complex and is composed of four distinct chains.
The rodent expresses a functional chimeric T cell co-receptor polypeptide.
The drug can reduce CCR5 viral co-receptor expressed in T lymphocytes and monocytes at a transcriptional level.
The nucleotide sequence is present at an endogenous T cell co-receptor locus.
This co-receptor molecule is αv integrin.
Only cells expressing both CD4 and a functional co-receptor for HIV become infected.
CCR5 is the major co-receptor used by HIV to infect cells of the immune system.
In one aspect, endoglin is a TGFbeta co-receptor.
Affinity methods may utilize anti-CD4 co-receptor antibodies as the source of affinity reagent.
In one embodiment, endoglin is a TGFbeta co-receptor.
The first co-receptor that HIV anchors to is known as CCR5.
The prediction on maintaining or switching hiv-1 co-receptor usage over time is still uncertain.
The CD4 functions as an adhesion molecule and as a co-signaling co-receptor.
The X4 co-receptor is found both within and outside of the immune system,.
Alternatively, zcyto20 polypeptide may compete for a viral receptor or co-receptor to block viral infection.
CD4, a co-receptor of the TCR complex, also binds to a different section of the MHC molecule.
Similar results were obtained when performing the assay with the GFRa1 co-receptor ( data not shown ).
Currently the CCR5 co-receptor has emerged as a potential target for anti-HIV chemotherapy D.
In a related embodiment, viruses that use the CXCR4 co-receptor are identified.
Co-receptor Tropism Screening Assay . In this figure, the assays is performed using two cell lines.
In one embodiment, viruses that use the CCR5 co-receptor are identified.
Figure 8, Inhibition by Co-Receptor Antagonists and R5 inhibition is shown following administration of co-reccptor antagonists.
In yet another embodiment, the viral entry inhibitor is a CXCR4 co-receptor antagonist.
Inhibition by Co-Receptor Antagonists.
These methods may be for accurately and reproducibly measuring HIV-1 co-receptor tropism.
In addition to CD4, HIV requires a co-receptor for entry into target cells.
The term " GAG binding protein " relates to any protein which binds to a GAG co-receptor.
In a preferred method, the immunodeficiency virus co-receptor is a CCR5 or CXCR4 polypeptide sequence.
These cells are unresponsive to FGF21 until transfected with the co-receptor BKL.
These results indicate that the gp120 co-receptor binding site is important for binding to co-receptor.
In one embodiment, the non-human animal expresses a functional chimeric T cell co-receptor polypeptide.
Most HIV-based co-receptor research focuses on the CCR5 co-receptor.
