Examples of 'cocrystal' in a sentence
Meaning of "cocrystal"
cocrystal (noun) - a solid material composed of two or more different molecules that are in a crystal lattice. It is formed by the interaction of the molecules through noncovalent bonds
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- A crystal, often a large-molecule crystal, having two or more distinct molecular components within the crystal lattice.
How to use "cocrystal" in a sentence
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cocrystal
In another embodiment the molecular complex is a cocrystal.
The meaning of the term cocrystal is subject of disagreement.
A cocrystal of metronidazole and gentisic acid.
Cooling molten mixture of cocrystal formers often affords cocrystals.
Cocrystal of agomelatine with phosphoric acid.
In one embodiment the cocrystal comprises bilastine and resorcinol.
A cocrystal of tiotropium bromide and lactose monohydrate is herein disclosed.
By doing this one can create a cocrystal with specific properties.
The cocrystal is shown to have distinct physicochemical properties.
The peaks within this plot may be used to characterize a cocrystal.
The cocrystal of the present invention is not a salt.
In a particular embodiment the at least one cocrystal forming compound is a phenolic compound.
A cocrystal of metronidazole and gallic acid.
Nifuratel sulfoxide or a physiologically acceptable salt thereof or a physiologically acceptable cocrystal thereof.
Cocrystal structures have also become a staple for drug discovery.
See also
In one embodiment the cocrystal comprises bilastine and sorbic acid.
A cocrystal may also be used to isolate or purify a compound during manufacturing.
In one embodiment the cocrystal comprises bilastine and adipic acid.
Cocrystal metalaxyl and prothioconazole compounds and compositions thereof are described herein.
In one embodiment the cocrystal comprises bilastine and succinic acid.
The disclosure also provides for a method of making a metalaxyl and prothioconazole cocrystal by.
In one embodiment the cocrystal comprises bilastine and benzoic acid.
The present invention also refers to a process for preparing a cocrystal according to the invention.
A preferred cocrystal is one of stable form having a suitable melting point.
The preparation and characterization of each cocrystal is described in the examples below.
The cocrystal and cocrystal salt can be produced by cocrystallization known per se.
The guest is present in order to form the cocrystal with the active agent.
The seeding cocrystal form may be obtained by any of the processes described above.
Such suitable crystalline forms may be obtained by forming a cocrystal between the drug and a coformer.
The cocrystal or a salt thereof can be produced according to a cocrystallization a method known per se.
The present invention also relates to a pharmaceutical composition comprising the above cocrystal as active ingredient.
In one embodiment the cocrystal comprises bilastine and glutaric acid.
The stoichiometric ratio of an API to coformer is a generally unpredictable feature of a cocrystal.
Aqueous cocrystal solubility can be orders of magnitude higher than that of the constituent drug.
Particular embodiments In one embodiment the cocrystal comprises bilastine and glutaric acid.
The cocrystal and cocrystal salt can be produced according to a cocrystallization method known per se.
In one embodiment, the novel cocrystal is anhydrous.
This cocrystal Form I is easy to handle and shows crystal stability at room temperature.
The spectrum may be used to characterize cocrystal 3.
However, cocrystal formation is not predictable, and in fact is not always possible.
The traces may be used to characterize cocrystal 4.
Thus, in a cocrystal one component crystallizes with one or more neutral components.
Thus, these data characterize the cocrystal.
Powder dissolution of cocrystal 3 was attempted under the same experimental conditions as the cocrystal 4.
A composition consisting essentially of the cocrystal as claimed in claim 1.
Figure 1 is a powder diffraction pattern of the metronidazole, gentisic acid cocrystal.
The pterostilbene, caffeine cocrystal is polymorphic.
These techniques are used to generate data on a solid crystal, such as a cocrystal.
Figure 6 is an x-ray diffraction pattern of a cocrystal of metronidazole with gallic acid.
In some instances the API-amino acid molecular complex is a cocrystal.
