Examples of 'cohesin' in a sentence
Meaning of "cohesin"
cohesin (noun): Cohesin is a protein complex involved in the process of cell division
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- Any of a class of proteins responsible for binding the sister chromatids during mitosis
How to use "cohesin" in a sentence
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cohesin
High levels of cohesin binding are observed at the centromere.
Red regions are linkers spacing some of the cohesin domains.
Deciphering cohesin regulation is thus fundamental to understand chromosome biology.
Two independent modes of chromatin organization revealed by cohesin removal.
It is not clear how the cohesin ring links sister chromatids together.
This provides two layers of negative regulation to prevent inappropriate cohesin cleavage.
It does this by preventing the cohesin complex which regulates chromatid separation from prematurely dissociating.
Alterations in this process may interfere with normal sorting mechanisms offered by cohesin.
This results in free separase that is able to destroy cohesin and initiate chromosome separation.
These sites are correlated with association of CTCF and the cohesin.
Wapl has been tied to the loss of cohesin from the chromatids during M phase.
Thus both Cohesin and Dockerin domains are readily expressed as rAb fusion proteins.
This study opens large perspectives towards a better understanding of cohesin regulation in genome organisation.
Cohesin is a ring-shaped protein complex responsible for sister chromatid cohesion.
At this stage, the centromeres are still attached by the protein cohesin.
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However, cohesin has since been linked to many more functions within the cell.
In animal cells, however, the bulk of cohesin dissociates from chromosomes during prophase.
The cohesin complex is remarkably long-lived but eventually lost irreversibly from chromosomes.
Investigators unexpectedly found recurring mutations in cohesin genes, which are important in cell division.
Stag2 encodes a cohesin protein responsible for holding sister chromatids together pre-anaphase.
This regulation relies in part on the control of cohesin binding to chromatin ( DNA capture ).
The cohesin complex is established during the initial stages of S-phase.
As previously described in mammals, Wpl1 counteracts loop expansion by dissociating cohesin from DNA.
One of these cohesin proteins crucial for sister chromatid cohesion is Scc1.
During this thesis, we focused on Cohesin and Condensin.
Cohesin complexes must be present during S-phase in order for cohesion to take place.
Once cells start replicating their DNA, cohesin rings close and link the sister chromatids together.
Pds5 interacts with chromatin-associated cohesin.
During metaphase, centromeric cohesin is protected by the shugoshin-PP2A complex.
Cohesin contains SMC1 and SMC3 and is involved in sister chromatid cohesion.
It is unclear, however, how cohesin is loaded on the chromosomes during G1.
The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex.
Fig . 7, Separase cleavage of the cohesin Rec8 is necessary during meiotic nuclear divisions.
The cohesin ring has many functions, 1.
When Scc1 binds on both Smc1 and Smc3, the cohesin complex forms a closed ring structure.
Fig . 10, Ectopically expressed SCC1-myc is incorporated into the cohesin complex and is cleaved in mitosis.
The position of 9S and 14S cohesin complexes is indicated.
