Examples of 'coiled-coil' in a sentence
Meaning of "coiled-coil"
coiled-coil (noun) - a structural motif in proteins where two or more alpha helices wrap around each other in a coiled manner
How to use "coiled-coil" in a sentence
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coiled-coil
Shaded boxes indicate coiled-coil regions.
Coiled-coil structures are found in many types of proteins.
This gene encodes a protein containing a coiled-coil domain.
A coiled-coil domain is different from a leucine zipper.
The basic unit of these structures is a coiled-coil dimer.
Disruption in the coiled-coil segments of the protein is evident.
The polycystins form a complex via their coiled-coil domains.
Special instructions for coiled-coil filaments are under consideration.
A neck region as used herein may comprise a coiled-coil structure.
The second coiled-coil region preferably includes a leucine zipper motif.
This conforms to the conventions used in the coiled-coil literature.
Preferred coiled-coil domains are those taken from bacterial transmembrane proteins.
A common structural motif involved in protein oligomerisation is the coiled-coil domain.
Additional instructions for coiled-coil filament are under consideration.
When the fine wire is absent, the electrode is referred to as a coiled-coil electrode.
See also
For coiled-coil filaments, the turns are defined by the envelope of the primary coil.
These positions lie along the outward face of a coiled-coil heterodimer.
Common to all of them is a coiled-coil domain which plays a key role in heterotrimer assembly.
The polypeptides of this invention are designed to dimerize with a coiled-coil motif in aqueous environments.
The coiled-coil domain mediates its oligomerization which is necessary for its activities.
The arrows define the limits of the coiled-coil and fibrinogen like domains.
The fusión gene has a protein tyrosine kinase domain together with a coiled-coil domain.
The coiled-coil spacer domain provides numerous advantages over the spacers previously described in the art.
The primary structure may allow the protein to form a coiled-coil structure in solution.
The endodomain of a coiled-coil spacer CAR may be or comprise an intracellular signalling domain.
An oligomeric fusión protein will be stabilized by the coiled-coil interaction of leucine zipper domain.
A coiled-coil region adjacent to the MATH domain is also important for the trimerisation.
It is also predicted that this protein form a dimer through its coiled-coil rod domain.
It forms an antiparallel coiled-coil fold termed an ACC finger.
More preferably the linkers or spacers have been used to link proteins comprising coiled-coil structures.
An ACID peptide can form an a-helical coiled-coil conformation with a BASE peptide.
Applicants have used a combination of hydrophobic interactions and electrostatic interactions to stabilize the coiled-coil conformation.
Each polypeptide making up the coiled-coil spacer CAR comprises four separate AD1 domains.
Leucine zippers heterodimerise in the dimerization potion of the sequence, whereas coiled-coil domains homodimerise.
A preferred coiled-coil presentation structure is as follows,.
Interestingly, specific mutations affecting the coiled-coil motif cause ADPKD in humans.
Coiled-coil filament lamp.
The predicted alpha helical regions in Figure 4 generally correspond to the previously noted coiled-coil regions.
A potential coiled-coil domain.
The structure has a YadA-like head domain and an extended coiled-coil stalk.
It contains a coiled-coil domain, hence the current origin of its name.
The structure is a right-handed alpha helical coiled-coil structure.
In some instances, the coiled-coil peptides are ACID-BASE peptides.
In the second design, peptides are used which can form so-called coiled-coil structures.
Within NadA, the boundaries of the coiled-coil domain are given in reference 4.
The coiled-coil regions identified within GAS 40 are likely to form alpha helical coils.
Further, the optimal number of hepta-d-repeats in the coiled-coil zipper motif are difficult to determine.
Transmembrane and coiled-coil domains 5A is a protein that in humans is encoded by the TMCO5A gene.
Members of the superfamily have a characteristic helical / jelly-roll fold and a coiled-coil homotrimeric structure.
At the N-terminal end of the coiled-coil rod, there is also a hypervariable region.
